公开(公告)号：US11753616B2

公开(公告)日：2023-09-12

申请号：US15313812

申请日：2015-05-27

申请人： DNA Genotek Inc.

发明人： H. Chaim Birnboim ,  Cassandra Kelly-Cirino ,  Bitapi Ray ,  Jacques Oscar Everard Niles ,  Olle Maarten de Bruin

IPC分类号： C12N1/04 ,  C12N1/20 ,  C12Q1/24 ,  C12Q1/00

CPC分类号： C12N1/20 ,  C12N1/04 ,  C12Q1/00 ,  C12Q1/24

摘要： The present application is to provide a composition and method for stabilizing and maintaining the viability of hardy microorganisms from sample collection to downstream analysis. In particular, there is a method for preserving viable hardy bacteria, such as Mycobacteria, Bacillus anthracis, or Clostridium difficile, in a biological sample, comprising contacting the biological sample with a stabilization composition, wherein the stabilization composition comprises a chelating agent, a denaturing, a salt and has a pH between about 6 and about 11.

公开(公告)号：US20170226469A1

公开(公告)日：2017-08-10

申请号：US15313812

申请日：2015-05-27

申请人： DNA Genotek Inc.

发明人： H. Chaim Birnboim ,  Cassandra Kelly-Cirino ,  Bitapi Ray ,  Jacques Oscar Everard Niles ,  Olle Maarten de Bruin

IPC分类号： C12N1/20 ,  C12Q1/24 ,  C12Q1/00 ,  C12N1/04

CPC分类号： C12N1/20 ,  C12N1/04 ,  C12Q1/00 ,  C12Q1/24

摘要： The present application is to provide a composition and method for stabilizing and maintaining the viability of hardy microorganisms from sample collection to downstream analysis. In particular, there is a method for preserving viable hardy bacteria, such as Mycobacteria, Bacillus anthracis, or Clostridium difficile, in a biological sample, comprising contacting the biological sample with a stabilization composition, wherein the stabilization composition comprises a chelating agent, a denaturing, a salt and has a pH between about 6 and about 11.

公开(公告)号：US20230416671A1

公开(公告)日：2023-12-28

申请号：US18465939

申请日：2023-09-12

申请人： DNA Genotek Inc.

发明人： H. Chaim Birnboim ,  Cassandra Kelly-Cirino ,  Bitapi Ray ,  Jacques Oscar Everard Niles ,  Olle Maarten de Bruin

IPC分类号： C12N1/20 ,  C12Q1/00 ,  C12N1/04 ,  C12Q1/24

CPC分类号： C12N1/20 ,  C12Q1/00 ,  C12N1/04 ,  C12Q1/24

摘要： The present application is to provide a composition and method for stabilizing and maintaining the viability of hardy microorganisms from sample collection to downstream analysis. In particular, there is a method for preserving viable hardy bacteria, such as Mycobacteria, Bacillus anthracis, or Clostridium difficile, in a biological sample, comprising contacting the biological sample with a stabilization composition, wherein the stabilization composition comprises a chelating agent, a denaturing, a salt and has a p H between about 6 and about 11.