公开(公告)号：US20160333058A1

公开(公告)日：2016-11-17

申请号：US15112911

申请日：2015-01-29

Applicant: Jessica Leigh MC GRATH ,  Bastien CHEVREUX ,  Peter Scott YORGEY ,  DSM IP ASSETS B.V.

Inventor： Jessica Leigh MC GRATH ,  Bastien CHEVREUX ,  Peter Scott YORGEY

IPC: C07K14/39 ,  C12N15/81 ,  C12P23/00

Abstract: The present invention relates to the use of novel promoters for heterologous gene expression, preferably for expression of genes in organisms of the genus Yarrowia, to the genetically modified organisms of the genus Yarrowia, and to a process for producing biosynthetic products by cultivating the genetically modified organisms.

Abstract translation: 本发明涉及用于异源基因表达的新型启动子，优选用于在耶氏酵母属的生物体中表达基因到耶氏酵母属的转基因生物的用途，以及通过培养经遗传修饰的生物合成产物的方法 生物体。

公开(公告)号：US20250109422A1

公开(公告)日：2025-04-03

申请号：US18834722

申请日：2023-02-01

Applicant: DSM IP ASSETS B.V.

Inventor： Peter Louis HOUSTON ,  Maria Elena MAYORGA ,  Valmik Kanubhai VYAS ,  Peter Scott YORGEY

IPC: C12P23/00 ,  C12N1/06 ,  C12N9/10 ,  C12N15/81

Abstract: The present invention is related to a novel process on biological production of lipophilic substances in an oleaginous host cell, particularly Yarrowia lipolytica, comprising modification in the N-glycosylation pathway, leading to higher yield and product purity with further facilitating the overall production process.