公开(公告)号：US08436312B2

公开(公告)日：2013-05-07

申请号：US12999041

申请日：2008-10-08

申请人： Naoko Inadama ,  Hideo Murayama ,  Kengo Shibuya ,  Fumihiko Nishikido ,  Taiga Yamaya ,  Eiji Yoshida

发明人： Naoko Inadama ,  Hideo Murayama ,  Kengo Shibuya ,  Fumihiko Nishikido ,  Taiga Yamaya ,  Eiji Yoshida

IPC分类号： G01T1/20

CPC分类号： G01T1/1644 ,  G01T1/2008

摘要： This aims to provide a DOI type radiation detector in which scintillation crystals arranged two-dimensionally on a light receiving surface to form rectangular section groups in extending directions of the light receiving surface of a light receiving element are stacked up to make a three-dimensional arrangement and responses of the crystals that have detected radiation are made possible to identify at response positions on the light receiving surface, so that a three-dimensional radiation detection position can be obtained. In the DOI type radiation detector, scintillation crystals are right triangle poles extending upwards from the light receiving surface and the response positions on the light receiving surface are characterized. With this structure, DOI identification of a plurality of layers can be carried out by simply performing an Anger calculation of a light receiving element signal.

摘要翻译： 其目的在于提供一种DOI型放射线检测器，其中，在光接收表面上二维布置的闪烁晶体在光接收元件的光接收表面的延伸方向上形成矩形截面组，以形成三维布置 并且能够检测到辐射的晶体的响应可以在光接收表面上的响应位置处识别，从而可以获得三维辐射检测位置。 在DOI型辐射检测器中，闪烁晶体是从光接收表面向上延伸的直角三角形磁极，并且在光接收表面上的响应位置被表征。 利用这种结构，可以通过简单地执行光接收元件信号的愤怒计算来执行多个层的DOI识别。

公开(公告)号：US20120165651A1

公开(公告)日：2012-06-28

申请号：US13257526

申请日：2009-03-23

申请人： Taiga Yamaya ,  Eiji Yoshida ,  Fumihiko Nishikido ,  Taku Inaniwa ,  Hideo Murayama

发明人： Taiga Yamaya ,  Eiji Yoshida ,  Fumihiko Nishikido ,  Taku Inaniwa ,  Hideo Murayama

IPC分类号： A61B6/00

CPC分类号： A61N5/1049 ,  A61B6/037 ,  A61N2005/1052 ,  A61N2005/1087 ,  G01T1/1603 ,  G01T1/2985

摘要： An imaging device, or a PET device, opposed gamma camera type PET device, or open PET device in particular, that is combined with a radiation therapy device, in which detectors are rotated to reduce incidence of nuclear fragments on the detectors. For example, in an opposed gamma camera type PET device, beam irradiation and detector rotation can be synchronized to prevent the detectors from interfering with the treatment beam and reduce the incidence of nuclear fragments on the detectors. This makes it possible to reduce the incidence of nuclear fragments on the detectors without interfering with a treatment beam, thereby enabling measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or during irradiation.

摘要翻译： 与成像装置或PET装置相对的γ相机型PET装置或特别是开放的PET装置，其与辐射治疗装置组合，其中检测器被旋转以减少检测器上的核碎片的发生率。 例如，在相对的γ照相机类型的PET装置中，可以同步束照射和检测器旋转，以防止检测器干扰处理束并减少检测器上核碎片的发生。 这使得可以在不干扰处理束的情况下降低检测器上核碎片的发生率，从而能够在照射后或照射期间立即测量湮灭辐射和照射场的三维成像。

公开(公告)号：US08188437B2

公开(公告)日：2012-05-29

申请号：US12450529

申请日：2007-08-30

申请人： Eiji Yoshida ,  Kengo Shibuya ,  Taiga Yamaya ,  Hideo Murayama ,  Keishi Kitamura

发明人： Eiji Yoshida ,  Kengo Shibuya ,  Taiga Yamaya ,  Hideo Murayama ,  Keishi Kitamura

IPC分类号： G01T1/166

CPC分类号： G01T1/2985 ,  A61B6/037 ,  G01T1/1647

摘要： Upon detection of radiation by using a (three-dimensional) detector capable of distinguishing a detection position in a depth direction and energy, an energy window for distinguishing between a signal and noise is changed depending on the detection position in the depth direction, thus making it possible to obtain scattering components inside the detector. Alternatively, a weight is given to a detection event depending on the detection position in the depth direction and energy information to obtain scattering components inside the detector. Thereby, scattering components inside the detector can be obtained to increase the sensitivity of the detector. In this case, different detecting elements can be used depending on the detection position in the depth direction.

摘要翻译： 通过使用能够区分深度方向的检测位置和能量的（三维）检测器来检测辐射，根据深度方向的检测位置来改变用于区分信号和噪声的能量窗，从而使 可能在检测器内部获得散射成分。 或者，根据深度方向上的检测位置和能量信息给予检测事件的权重，以获得检测器内部的散射成分。 因此，可以获得检测器内部的散射分量，以提高检测器的灵敏度。 在这种情况下，根据深度方向的检测位置，可以使用不同的检测元件。

公开(公告)号：US20100046818A1

公开(公告)日：2010-02-25

申请号：US12450349

申请日：2007-03-30

申请人： Taiga Yamaya ,  Hideo Murayama ,  Eiji Yoshida

发明人： Taiga Yamaya ,  Hideo Murayama ,  Eiji Yoshida

IPC分类号： G06K9/00 ,  G08B21/00

CPC分类号： G01T1/1648 ,  G06T11/006 ,  G06T2211/424 ,  H04N5/32 ,  H04N5/367

摘要： In a case where an error is included in measurement data corresponding to one or a plurality of detecting elements in a tomography scanner, a system matrix to be calculated or referenced on image reconstruction calculation is corrected in accordance with the error. Thus, even when an error such as a defect or a fault occurs in a detector, influence of the error is eliminated, thereby reducing an artifact generated in an image. At that time, positional information of the detecting elements including the error and information on the degree of the error are stored in a storage device and referenced inside image reconstruction software, thus making it possible to correct the system matrix in accordance with the error.

摘要翻译： 在与断层摄影扫描仪中的一个或多个检测元件相对应的测量数据中包含误差的情况下，根据误差校正要在图像重建计算中计算或参考的系统矩阵。 因此，即使当在检测器中发生诸如缺陷或故障的错误时，也消除了误差的影响，从而减少了图像中产生的伪影。 此时，包括误差的检测元件的位置信息和关于误差的信息的信息被存储在存储装置中并被引用到图像内重建软件中，从而可以根据该错误来校正系统矩阵。

公开(公告)号：US09029789B2

公开(公告)日：2015-05-12

申请号：US12919358

申请日：2008-04-09

申请人： Kengo Shibuya ,  Taiga Yamaya ,  Naoko Inadama ,  Fumihiko Nishikido ,  Eiji Yoshida ,  Hideo Murayama

发明人： Kengo Shibuya ,  Taiga Yamaya ,  Naoko Inadama ,  Fumihiko Nishikido ,  Eiji Yoshida ,  Hideo Murayama

IPC分类号： G01T1/202 ,  G01T1/29

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： A light receiver for detecting incident time is installed on the side of a radiation source of a scintillator (including a Cherenkov radiation emitter), and information (energy, incident time, an incident position, etc.) on radiation made incident into the scintillator is obtained by the output of the light receiver. It is, thereby, possible to identify an incident position and others of radiation into the scintillator at high accuracy.

摘要翻译： 用于检测入射时间的光接收器安装在闪烁体（包括切伦科夫辐射发射器）的辐射源的一侧，并且入射到闪烁体中的辐射的信息（能量，入射时间，入射位置等）是 通过光接收器的输出获得。 因此，可以以高精度将入射位置和其他辐射识别到闪烁体中。

公开(公告)号：US20130009064A1

公开(公告)日：2013-01-10

申请号：US13635753

申请日：2010-03-25

申请人： Eiji Yoshida ,  Taiga Yamaya

发明人： Eiji Yoshida ,  Taiga Yamaya

IPC分类号： G01T1/164

CPC分类号： G01T1/2985

摘要： In a coincidence determination processing of a PET device for regarding and counting a pair of annihilation radiations detected within a predetermined time as occurring from the same nuclide, a priority of a line of response to acquire is set and a true coincidence is extracted from multiple coincidences by using information on a detection time difference if a plurality of coincidences are detected with the predetermined time. Consequently, a true coincidence is extracted from multiple coincidences which have heretofore been discarded. This improves detection sensitivity at high radioactive concentration and contributes to an improved dynamic range.

摘要翻译： 在从同一个核素发生的在预定时间内检测到的一对湮灭辐射的关联和计数的PET装置的重合确定处理中，设置对获取的响应行的优先级，并且从多个重合中提取真正的重合 如果在预定时间内检测到多个重合，则通过使用关于检测时间差的信息。 因此，从以前被丢弃的多个巧合中提取出真正的符合性。 这提高了在高放射性浓度下的检测灵敏度，并有助于改善动态范围。

公开(公告)号：US07671339B2

公开(公告)日：2010-03-02

申请号：US11658699

申请日：2006-12-25

申请人： Kengo Shibuya ,  Tomoaki Tsuda ,  Fumihiko Nishikido ,  Naoko Inadama ,  Eiji Yoshida ,  Taiga Yamaya ,  Hideo Murayama

发明人： Kengo Shibuya ,  Tomoaki Tsuda ,  Fumihiko Nishikido ,  Naoko Inadama ,  Eiji Yoshida ,  Taiga Yamaya ,  Hideo Murayama

IPC分类号： G01T1/164 ,  G01T1/166

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： A positron emission tomography (PET) scanner is provided which uses information on the time-of-flight difference (TOF) between annihilation radiations for image reconstruction. The scanner has detection time correction information (memory) corresponding to information on coordinates in a radiation detection element (e.g., scintillator crystal), in the depth and lateral directions, at which an interaction has occurred between an annihilation radiation and the crystal. Reference is made to the detection time correction information, thereby providing information on time-of-flight difference with improved accuracy. As such, an improved signal to noise ratio and spatial resolution are provided for image reconstruction using time-of-flight (TOF) difference.

摘要翻译： 提供了一种正电子发射断层扫描仪（PET）扫描仪，其使用关于图像重建的湮灭辐射之间的飞行时间差（TOF）的信息。 扫描仪具有与在湮灭辐射与晶体之间发生相互作用的深度和横向上的放射线检测元件（例如，闪烁体晶体）中的坐标信息相对应的检测时间校正信息（存储器）。 参考检测时间校正信息，从而提供关于飞行时间差异的信息，提高精度。 因此，为使用飞行时间（TOF）差异的图像重建提供了改善的信噪比和空间分辨率。

公开(公告)号：US20090159804A1

公开(公告)日：2009-06-25

申请号：US11658699

申请日：2006-12-25

申请人： Kengo Shibuya ,  Tomoaki Tsuda ,  Fumihiko Nishikido ,  Naoko Inadama ,  Eiji Yoshida ,  Taiga Yamaya ,  Hideo Murayama

发明人： Kengo Shibuya ,  Tomoaki Tsuda ,  Fumihiko Nishikido ,  Naoko Inadama ,  Eiji Yoshida ,  Taiga Yamaya ,  Hideo Murayama

IPC分类号： G01T1/164

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： A positron emission tomography (PET) scanner is provided which uses information on the time-of-flight difference (TOF) between annihilation radiations for image reconstruction. The scanner has detection time correction information (memory) corresponding to information on coordinates in a radiation detection element (e.g., scintillator crystal), in the depth and lateral directions, at which an interaction has occurred between an annihilation radiation and the crystal. Reference is made to the detection time correction information, thereby providing information on time-of-flight difference with improved accuracy. As such, an improved signal to noise ratio and spatial resolution are provided for image reconstruction using time-of-flight (TOF) difference.

摘要翻译： 提供了一种正电子发射断层扫描仪（PET）扫描仪，其使用关于图像重建的湮灭辐射之间的飞行时间差（TOF）的信息。 扫描仪具有与在湮灭辐射与晶体之间发生相互作用的深度和横向上的放射线检测元件（例如，闪烁体晶体）中的坐标信息相对应的检测时间校正信息（存储器）。 参考检测时间校正信息，从而提供关于飞行时间差异的信息，提高精度。 因此，为使用飞行时间（TOF）差异的图像重建提供了改善的信噪比和空间分辨率。

公开(公告)号：US20110001049A1

公开(公告)日：2011-01-06

申请号：US12919358

申请日：2008-04-09

申请人： Kengo Shibuya ,  Taiga Yamaya ,  Naoko Inadama ,  Fumihiko Nishikido ,  Eiji Yoshida ,  Hideo Murayama

发明人： Kengo Shibuya ,  Taiga Yamaya ,  Naoko Inadama ,  Fumihiko Nishikido ,  Eiji Yoshida ,  Hideo Murayama

IPC分类号： G01T1/20 ,  G01T1/161

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： A light receiver for detecting incident time is installed on the side of a radiation source of a scintillator (including a Cherenkov radiation emitter), and information (energy, incident time, an incident position, etc.) on radiation made incident into the scintillator is obtained by the output of the light receiver. It is, thereby, possible to identify an incident position and others of radiation into the scintillator at high accuracy.

摘要翻译： 用于检测入射时间的光接收器安装在闪烁体（包括切伦科夫辐射发射器）的辐射源的一侧，并且入射到闪烁体中的辐射的信息（能量，入射时间，入射位置等）是 通过光接收器的输出获得。 因此，可以以高精度将入射位置和其他辐射识别到闪烁体中。

公开(公告)号：US20100032574A1

公开(公告)日：2010-02-11

申请号：US12450529

申请日：2007-08-30

申请人： Eiji Yoshida ,  Kengo Shibuya ,  Taiga Yamaya ,  Hideo Murayama ,  Keishi Kitamura

发明人： Eiji Yoshida ,  Kengo Shibuya ,  Taiga Yamaya ,  Hideo Murayama ,  Keishi Kitamura

IPC分类号： G01T1/20 ,  G01T1/164

CPC分类号： G01T1/2985 ,  A61B6/037 ,  G01T1/1647

摘要： Upon detection of radiation by using a (three-dimensional) detector capable of distinguishing a detection position in a depth direction and energy, an energy window for distinguishing between a signal and noise is changed depending on the detection position in the depth direction, thus making it possible to obtain scattering components inside the detector. Alternatively, a weight is given to a detection event depending on the detection position in the depth direction and energy information to obtain scattering components inside the detector. Thereby, scattering components inside the detector can be obtained to increase the sensitivity of the detector. In this case, different detecting elements can be used depending on the detection position in the depth direction.

摘要翻译： 通过使用能够区分深度方向的检测位置和能量的（三维）检测器来检测辐射，根据深度方向上的检测位置来改变用于区分信号和噪声的能量窗口，从而使 可能在检测器内部获得散射成分。 或者，根据深度方向上的检测位置和能量信息给予检测事件的权重，以获得检测器内部的散射成分。 因此，可以获得检测器内部的散射分量，以提高检测器的灵敏度。 在这种情况下，根据深度方向的检测位置，可以使用不同的检测元件。