公开(公告)号：US20100040623A1

公开(公告)日：2010-02-18

申请号：US12442177

申请日：2006-12-20

申请人： Elisabeth Bock ,  Vladimir Berezin ,  Darya Kiryushko

发明人： Elisabeth Bock ,  Vladimir Berezin ,  Darya Kiryushko

IPC分类号： A61K39/395 ,  C07K7/06 ,  C07K7/08 ,  C07K14/00 ,  A61K38/08 ,  A61K38/10 ,  A61K38/16 ,  C07K16/00

CPC分类号： C07K14/4728 ,  A61K38/00

摘要： The present invention relates to peptide fragments derived from proteins of the S-100 family promoting neural cell survival, differentiation and proliferation. The invention further relates to pharmaceutical compositions comprising said peptide fragments and uses thereof for treatment of diseases and conditions where the effects of stimulating neural cell proliferation, differentiation and/or survival, and/or stimulating neural plasticity associated with learning and memory are beneficial for treatment.

摘要翻译： 本发明涉及衍生自S-100家族蛋白质的肽片段，促进神经细胞存活，分化和增殖。 本发明还涉及包含所述肽片段的药物组合物及其用于治疗刺激神经细胞增殖，分化和/或存活和/或刺激与学习和记忆相关的神经可塑性的作用对治疗有益的疾病和病症的用途 。