公开(公告)号：US20240165121A1

公开(公告)日：2024-05-23

申请号：US18188700

申请日：2023-03-23

Applicant: Epizyme, Inc.

Inventor： Kevin Wayne KUNTZ ,  John Emmerson Campbell ,  Masashi Seki ,  Syuji Shirotori ,  Wataru Itano ,  Wanjun Zheng

IPC: A61K31/5377 ,  A61K31/4412 ,  A61K31/4545 ,  A61K31/5375 ,  C07D213/64 ,  C07D401/12 ,  C07D405/12 ,  C07D405/14

CPC classification number: A61K31/5377 ,  A61K31/4412 ,  A61K31/4545 ,  A61K31/5375 ,  C07D213/64 ,  C07D401/12 ,  C07D405/12 ,  C07D405/14

Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

公开(公告)号：US20210060027A1

公开(公告)日：2021-03-04

申请号：US16924962

申请日：2020-07-09

Applicant: Epizyme, Inc.

Inventor： Kevin Wayne Kuntz ,  John Emmerson Campbell ,  Masashi Seki ,  Syuji Shirotori ,  Wataru Itano ,  Wanjun Zheng

IPC: A61K31/5377 ,  C07D405/14 ,  C07D213/64 ,  A61K31/5375 ,  A61K31/4412 ,  A61K31/4545 ,  C07D401/12 ,  C07D405/12

Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

公开(公告)号：US10092572B2

公开(公告)日：2018-10-09

申请号：US14435704

申请日：2013-10-15

Applicant: Epizyme, Inc.

Inventor： Kevin Wayne Kuntz ,  John Emmerson Campbell ,  Masashi Seki ,  Syuji Shirotori ,  Wataru Itano ,  Wanjun Zheng

IPC: C07D213/64 ,  A61K31/5377 ,  C07D405/14 ,  A61K31/5375 ,  A61K31/4412 ,  A61K31/4545 ,  C07D401/12 ,  C07D405/12

Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

公开(公告)号：US11642348B2

公开(公告)日：2023-05-09

申请号：US16924962

申请日：2020-07-09

Applicant: Epizyme, Inc.

Inventor： Kevin Wayne Kuntz ,  John Emmerson Campbell ,  Masashi Seki ,  Syuji Shirotori ,  Wataru Itano ,  Wanjun Zheng

IPC: C07D405/14 ,  C07D213/64 ,  C07D401/12 ,  C07D405/12 ,  A61K31/5377 ,  A61K31/5375 ,  A61K31/4412 ,  A61K31/4545

CPC classification number: A61K31/5377 ,  A61K31/4412 ,  A61K31/4545 ,  A61K31/5375 ,  C07D213/64 ,  C07D401/12 ,  C07D405/12 ,  C07D405/14

Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

公开(公告)号：US20150284370A1

公开(公告)日：2015-10-08

申请号：US14435704

申请日：2013-10-15

Applicant: EPIZYME, INC.

Inventor： Kevin Wayne Kuntz ,  John Emmerson Campbell ,  Masashi Seki ,  Syuji Shirotori ,  Wataru Itano ,  Wanjun Zheng

IPC: C07D405/14 ,  C07D401/12 ,  C07D405/12 ,  C07D213/64

CPC classification number: A61K31/5377 ,  A61K31/4412 ,  A61K31/4545 ,  A61K31/5375 ,  C07D213/64 ,  C07D401/12 ,  C07D405/12 ,  C07D405/14

Abstract: The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.