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公开(公告)号：US20110150997A1
公开(公告)日：2011-06-23
申请号：US11932267
申请日：2007-10-31
申请人： Gautam Shah , Gary Bubb , Maryam Ahmadi
发明人： Gautam Shah , Gary Bubb , Maryam Ahmadi
IPC分类号： A61K31/7068 , A61K9/14 , A61K9/20 , A61K9/32 , A61P31/18
CPC分类号： A61K31/7068 , A61K9/2054 , A61K9/2846 , A61K9/2886
摘要： The invention provides novel pharmaceutical compositions of Elvucitabine. The invention also provides pharmaceutical compositions and oral dosage forms having unique physical-chemical properties.
摘要翻译： 本发明提供了Elvucitabine的新型药物组合物。 本发明还提供具有独特物理化学性质的药物组合物和口服剂型。
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公开(公告)号：US09056054B2
公开(公告)日：2015-06-16
申请号：US13379481
申请日：2010-06-25
IPC分类号： A61K9/28 , A61K9/20 , A61K31/485
CPC分类号： A61K9/28 , A61K9/2027 , A61K9/2095 , A61K9/2846 , A61K9/2866 , A61K9/2873 , A61K9/2893 , A61K31/485
摘要： Aspects of the present invention are directed to abuse resistant oral dosage forms comprising a compressed microtablet that is coated with a water-retardant polymer. Additional aspects of the present invention are directed to an oral dosage form comprising an opioid agonist and at least one compressed microtablet coated with a water retardant polymer. The compressed microtablet may comprise an opioid antagonist.
摘要翻译： 本发明的方面涉及耐药性口服剂型，其包含用阻燃性聚合物涂覆的压缩微片。 本发明的另外的方面涉及包含阿片样物质激动剂和涂覆有阻燃聚合物的至少一个压缩微片的口服剂型。 压缩的微片可以包含阿片样物质拮抗剂。
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公开(公告)号：US20120189693A1
公开(公告)日：2012-07-26
申请号：US13379486
申请日：2010-06-25
IPC分类号： A61K9/20 , A61K9/36 , A61K31/485 , A61P25/04 , A61P29/00 , A61P33/10 , A61P9/06 , A61P31/04 , A61P31/12 , A61P7/02 , A61P25/24 , A61P3/10 , A61P25/08 , A61P31/10 , A61P19/06 , A61P9/12 , A61P25/06 , A61P35/00 , A61P15/10 , A61P37/06 , A61P33/02 , A61P5/14 , A61P25/22 , A61P25/20 , A61P25/18 , A61P9/04 , A61P25/16 , A61P1/00 , A61P9/10 , A61P21/02 , A61P19/10 , A61P3/04 , A61P25/28 , A61K9/28 , A61K9/42 , A61K9/38 , A61K9/34 , B29C59/02 , B29B9/00 , A61K9/32
CPC分类号： A61K9/2018 , A61J3/10 , A61K9/1623 , A61K9/1635 , A61K9/2027 , A61K9/2072 , A61K9/2095
摘要： Aspects of the present invention are directed to oral dosage forms comprising a compressed microtablet, wherein said microtablet has a major dimension that is between about 0.25 mm and about 1.0 mm and comprises at least about 0.01 weight percent of at least one pharmaceutically active agent that is distributed substantially throughout said microtablet. Additional aspects of the present invention are directed to methods for producing compressed microtablets having a major dimension that is between about 0.25 mm and about 1.0 mm.
摘要翻译： 本发明的方面涉及包含压缩微片的口服剂型，其中所述微片的主要尺寸为约0.25mm至约1.0mm，并且包含至少约0.01重量％的至少一种药物活性剂，其为 分布在整个所述微片上。 本发明的另外的方面涉及用于生产主要尺寸在约0.25mm至约1.0mm之间的压缩微片的方法。
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公开(公告)号：US20130084333A1
公开(公告)日：2013-04-04
申请号：US13379481
申请日：2010-06-25
IPC分类号： A61K9/28
CPC分类号： A61K9/28 , A61K9/2027 , A61K9/2095 , A61K9/2846 , A61K9/2866 , A61K9/2873 , A61K9/2893 , A61K31/485
摘要： Aspects of the present invention are directed to abuse resistant oral dosage forms comprising a compressed microtablet that is coated with a water-retardant polymer. Additional aspects of the present invention are directed to an oral dosage form comprising an opioid agonist and at least one compressed microtablet coated with a water retardant polymer. The compressed microtablet may comprise an opioid antagonist.
摘要翻译： 本发明的方面涉及耐药性口服剂型，其包含用阻燃性聚合物涂覆的压缩微片。 本发明的另外的方面涉及包含阿片样物质激动剂和涂覆有阻燃聚合物的至少一个压缩微片的口服剂型。 压缩的微片可以包含阿片样物质拮抗剂。
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