公开(公告)号：US20250061965A1

公开(公告)日：2025-02-20

申请号：US18941251

申请日：2024-11-08

Applicant: Genentech, Inc.

Inventor： Zia KHAN ,  Matthew Lawrence ALBERT ,  G Scott CHANDLER

IPC: G16B20/20 ,  G16B30/00 ,  G16H10/40 ,  G16H20/40 ,  G16H50/30

Abstract: Provided herein are diagnostic and therapeutic methods for the treatment of cancer using polygenic risk scores (PRSs) for dermatological autoimmune diseases. In particular, the invention provides methods for patient selection and methods of treatment.

公开(公告)号：US20230391875A1

公开(公告)日：2023-12-07

申请号：US18167295

申请日：2023-02-10

Applicant: Genentech, Inc.

Inventor： G Scott CHANDLER ,  Zia KHAN

IPC: C07K16/28 ,  C12Q1/6886 ,  A61K45/06

CPC classification number: C07K16/2827 ,  C12Q1/6886 ,  G01N2800/52 ,  G01N2800/7028 ,  A61K45/06

Abstract: Provided herein are diagnostic and therapeutic methods for the treatment of cancer using polygenic risk scores (PRSs) for endocrine diseases, including hypothyroidism. In particular, the invention provides methods for patient selection and methods of treatment.

公开(公告)号：US20220115087A1

公开(公告)日：2022-04-14

申请号：US17395996

申请日：2021-08-06

Applicant: Genentech, Inc.

Inventor： Zia KHAN ,  Matthew Lawrence ALBERT ,  G Scott CHANDLER

IPC: G16B20/20 ,  G16B30/00 ,  G16H50/30 ,  G16H10/40 ,  G16H20/40

Abstract: Provided herein are diagnostic and therapeutic methods for the treatment of cancer using polygenic risk scores (PRSs) for dermatological autoimmune diseases. In particular, the invention provides methods for patient selection and methods of treatment.