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Patent Agency Ranking
1.发明申请公开(公告)号：US20200155676A1
公开(公告)日：2020-05-21
申请号：US16453650
申请日：2019-06-26
Applicant: Genentech, Inc.
Inventor： Jane GROGAN , Yuanyuan XIAO , Patrick CAPLAZI , Steve LIANOGLOU , Jason HACKNEY , Eugene Yu-Chuan CHIANG
IPC: A61K39/395 , C07K16/28 , C07K16/24 , A61K47/62 , C07K16/30
Abstract: The present disclosure provides methods comprising administering to the individual an effective amount of a PD-1 axis binding antagonist and an IL-17 binding antagonist. Further provided are kits comprising a PD-1 axis binding antagonist, an IL-17 binding antagonist, or both, as well as instructions for use thereof.
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公开(公告)号：US20170037127A1
公开(公告)日：2017-02-09
申请号：US15239524
申请日：2016-08-17
Applicant: Genentech, Inc.
Inventor： Jane GROGAN , Robert J. JOHNSTON , Bryan IRVING , Jason HACKNEY , Xin YU , Dan EATON , Kristin BOWLES , Laetitia COMPS-AGRAR
CPC classification number: C07K16/2803 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0331 , A01K2267/0387 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/507 , C07K14/70596 , C07K16/2818 , C07K16/2827 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3053 , C07K16/3061 , C07K16/3069 , C07K2319/30 , Y02A50/466
Abstract: The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.
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3.发明申请METHODS OF TREATING CANCER USING PD-1 AXIS BINDING ANTAGONISTS AND TIGIT INHIBITORS 审中-公开使用PD-1轴绑定拮抗剂和TIGIT抑制剂治疗癌症的方法公开(公告)号：US20170044256A1
公开(公告)日：2017-02-16
申请号：US15239569
申请日：2016-08-17
Applicant: Genentech, Inc.
Inventor： Jane GROGAN , Robert J. JOHNSTON , Bryan IRVING , Jason HACKNEY , Xin YU , Dan EATON , Kristin BOWLES , Laetitia COMPS-AGRAR
IPC: C07K16/28 , A61K39/395 , C07K16/30 , A61K45/06
CPC classification number: C07K16/2803 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0331 , A01K2267/0387 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/507 , C07K14/70596 , C07K16/2818 , C07K16/2827 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3053 , C07K16/3061 , C07K16/3069 , C07K2319/30 , Y02A50/466
Abstract: The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.
Abstract translation: 本发明描述了包含PD-1轴结合拮抗剂和降低或抑制TIGIT表达和/或活性的试剂的组合治疗及其使用方法，包括治疗需要增强免疫原性的病症的方法，例如增加肿瘤免疫原性 治疗癌症或慢性感染。
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4.发明申请公开(公告)号：US20170274073A1
公开(公告)日：2017-09-28
申请号：US15448437
申请日：2017-03-02
Applicant: Genentech, Inc.
Inventor： Jane GROGAN , Yuanyuan XIAO , Patrick CAPLAZI , Steve LIANOGLOU , Jason HACKNEY , Eugene Yu-Chuan CHIANG
IPC: A61K39/395 , C07K16/30 , C07K16/28
CPC classification number: A61K39/39558 , A61K47/62 , A61K2039/505 , A61K2039/507 , A61K2300/00 , C07K16/244 , C07K16/2827 , C07K16/3053 , C07K2317/33
Abstract: The present disclosure provides methods comprising administering to the individual an effective amount of a PD-1 axis binding antagonist and an IL-17 binding antagonist. Further provided are kits comprising a PD-1 axis binding antagonist, an IL-17 binding antagonist, or both, as well as instructions for use thereof.
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5.发明申请METHODS OF TREATING CANCER USING PD-1 AXIS BINDING ANTAGONISTS AND TIGIT INHIBITORS 有权使用PD-1轴绑定拮抗剂和TIGIT抑制剂治疗癌症的方法公开(公告)号：US20150216970A1
公开(公告)日：2015-08-06
申请号：US14333375
申请日：2014-07-16
Applicant: GENENTECH, INC.
Inventor： Jane GROGAN , Robert J. JOHNSTON , Bryan IRVING , Jason HACKNEY , Xin YU , Dan EATON , Kristin BOWLES , Laetitia COMPS-AGRAR
IPC: A61K39/395 , A61K45/06
CPC classification number: C07K16/2803 , A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/0331 , A01K2267/0387 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/507 , C07K14/70596 , C07K16/2818 , C07K16/2827 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3053 , C07K16/3061 , C07K16/3069 , C07K2319/30 , Y02A50/466
Abstract: The present invention describes combination treatment comprising a PD-1 axis binding antagonist and an agent that decreases or inhibits TIGIT expression and/or activity and methods for use thereof, including methods of treating conditions where enhanced immunogenicity is desired such as increasing tumor immunogenicity for the treatment of cancer or chronic infection.
Abstract translation: 本发明描述了包含PD-1轴结合拮抗剂和降低或抑制TIGIT表达和/或活性的试剂的组合治疗及其使用方法，包括治疗需要增强免疫原性的病症的方法，例如增加肿瘤免疫原性 治疗癌症或慢性感染。
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