公开(公告)号：US20200155676A1

公开(公告)日：2020-05-21

申请号：US16453650

申请日：2019-06-26

Applicant: Genentech, Inc.

Inventor： Jane GROGAN ,  Yuanyuan XIAO ,  Patrick CAPLAZI ,  Steve LIANOGLOU ,  Jason HACKNEY ,  Eugene Yu-Chuan CHIANG

IPC: A61K39/395 ,  C07K16/28 ,  C07K16/24 ,  A61K47/62 ,  C07K16/30

Abstract: The present disclosure provides methods comprising administering to the individual an effective amount of a PD-1 axis binding antagonist and an IL-17 binding antagonist. Further provided are kits comprising a PD-1 axis binding antagonist, an IL-17 binding antagonist, or both, as well as instructions for use thereof.

公开(公告)号：US20170274073A1

公开(公告)日：2017-09-28

申请号：US15448437

申请日：2017-03-02

Applicant: Genentech, Inc.

Inventor： Jane GROGAN ,  Yuanyuan XIAO ,  Patrick CAPLAZI ,  Steve LIANOGLOU ,  Jason HACKNEY ,  Eugene Yu-Chuan CHIANG

IPC: A61K39/395 ,  C07K16/30 ,  C07K16/28

CPC classification number: A61K39/39558 ,  A61K47/62 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2300/00 ,  C07K16/244 ,  C07K16/2827 ,  C07K16/3053 ,  C07K2317/33

Abstract: The present disclosure provides methods comprising administering to the individual an effective amount of a PD-1 axis binding antagonist and an IL-17 binding antagonist. Further provided are kits comprising a PD-1 axis binding antagonist, an IL-17 binding antagonist, or both, as well as instructions for use thereof.