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公开(公告)号：US20210292440A1
公开(公告)日：2021-09-23
申请号：US17161068
申请日：2021-01-28
Applicant: Genentech, Inc.
Inventor： Mark Dennis , Ryan Jefferson Watts , Yunhua Yu Zuchero , Yin Zhang
Abstract: The present invention relates to antibodies that bind blood brain barrier receptors (BBB-R) and methods of using the same.
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公开(公告)号：US10941215B2
公开(公告)日：2021-03-09
申请号：US16131591
申请日：2018-09-14
Applicant: Genentech, Inc.
Inventor： Mark Dennis , Ryan Jefferson Watts , Yunhua Yu Zuchero , Yin Zhang
Abstract: The present invention relates to antibodies that bind blood brain barrier receptors (BBB-R) and methods of using the same.
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公开(公告)号：US20150353639A1
公开(公告)日：2015-12-10
申请号：US14761895
申请日：2013-05-20
Applicant: Genentech, Inc.
Inventor： Ryan Jefferson Watts , Joy Yu Zuchero , Jessica Couch , Mark Dennis
CPC classification number: A61K39/3955 , A61K35/18 , A61K39/39583 , A61K47/6849 , A61K47/6879 , A61K2039/505 , A61K2039/545 , C07K16/2881 , C07K16/40 , C07K16/44 , C07K16/468 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/52 , C07K2317/71 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C07K2319/30
Abstract: The present disclosure relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport.
Abstract translation: 本公开涉及用于改善血脑屏障受体介导的血脑屏障转运的安全性的组合物和方法。
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公开(公告)号：US20150329636A1
公开(公告)日：2015-11-19
申请号：US14577006
申请日：2014-12-19
Applicant: GENENTECH, INC.
Inventor： Mark Dennis , Ryan Jefferson Watts , Yunhua Joy Yu , Yin Zhang
CPC classification number: C07K16/468 , A61K47/68 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/2881 , C07K16/40 , C07K2317/31 , C07K2317/54 , C07K2317/70 , C07K2317/76 , C07K2317/92 , Y02A50/466
Abstract: The present invention relates to antibodies that bind blood brain barrier receptors (BBB-R) and methods of using the same.
Abstract translation: 本发明涉及结合血脑屏障受体（BBB-R）的抗体及其使用方法。
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Patent Agency Ranking
公开(公告)号：US08920805B2
公开(公告)日：2014-12-30
申请号：US13915363
申请日：2013-06-11
Applicant: Genentech, Inc.
Inventor： Yan Wu , Wei-Ching Liang , Ryan Jefferson Watts , Anil Durgadas
IPC: A61K39/395 , C07K16/28 , C07K16/22 , A61K39/00
CPC classification number: C07K16/2863 , A61K2039/505 , C07K16/22 , C07K2317/21 , C07K2317/31 , C07K2317/622 , C07K2317/76 , C07K2317/92
Abstract: The invention provides Nrp2 antagonists, such as anti-Nrp2 antibodies, and their use in the prevention and treatment of tumor metastasis.
Abstract translation: 本发明提供Nrp2拮抗剂，例如抗Nrp2抗体，以及它们在预防和治疗肿瘤转移中的用途。
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公开(公告)号：US11167038B2
公开(公告)日：2021-11-09
申请号：US16033489
申请日：2018-07-12
Applicant: Genentech, Inc.
Inventor： Ryan Jefferson Watts , Joy Yu Zuchero , Jessica Couch , Mark Dennis
Abstract: The present invention relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport.
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公开(公告)号：US20190030160A1
公开(公告)日：2019-01-31
申请号：US16033489
申请日：2018-07-12
Applicant: Genentech, Inc.
Inventor： Ryan Jefferson Watts , Joy Yu Zuchero , Jessica Couch , Mark Dennis
Abstract: The present invention relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport.
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公开(公告)号：US09611323B2
公开(公告)日：2017-04-04
申请号：US14577006
申请日：2014-12-19
Applicant: Genentech, Inc.
Inventor： Mark Dennis , Ryan Jefferson Watts , Yunhua Joy Yu , Yin Zhang
CPC classification number: C07K16/468 , A61K47/68 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/2881 , C07K16/40 , C07K2317/31 , C07K2317/54 , C07K2317/70 , C07K2317/76 , C07K2317/92 , Y02A50/466
Abstract: The present invention relates to antibodies that bind blood brain barrier receptors (BBB-R) and methods of using the same.
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公开(公告)号：US20140234312A1
公开(公告)日：2014-08-21
申请号：US13915363
申请日：2013-06-11
Applicant: Genentech, Inc.
Inventor： Yan Wu , Wei-Ching Liang , Ryan Jefferson Watts , Anil Durgadas
CPC classification number: C07K16/2863 , A61K2039/505 , C07K16/22 , C07K2317/21 , C07K2317/31 , C07K2317/622 , C07K2317/76 , C07K2317/92
Abstract: The invention provides Nrp2 antagonists, such as anti-Nrp2 antibodies, and their use in the prevention and treatment of tumor metastasis.
Abstract translation: 本发明提供Nrp2拮抗剂，例如抗Nrp2抗体，以及它们在预防和治疗肿瘤转移中的用途。
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