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公开(公告)号:US20180057604A1
公开(公告)日:2018-03-01
申请号:US15525821
申请日:2015-11-18
Applicant: Genentech, Inc. , Adimab LLC
Inventor: Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan WU , Eric Krauland , Michael Feldhaus , Yin Zhang , Joy Yu Zuchero , Jessica Couch , Mark S Dennis , James A Ernst , Gregory A Lazar
CPC classification number: C07K16/40 , A61K2039/505 , C07K16/22 , C07K16/2881 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C07K2319/00 , C12Y304/23046 , G01N33/6896 , G01N2333/70582 , G01N2333/96472 , G01N2800/28 , G01N2800/52
Abstract: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
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公开(公告)号:US20210087288A1
公开(公告)日:2021-03-25
申请号:US17008941
申请日:2020-09-01
Applicant: Genentech, Inc.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S. Dennis , James A. Ernst , Ryan J. Watts , Gregory A. Lazar
IPC: C07K16/28 , C07K16/40 , A61K47/68 , A61K39/395 , A61K45/06
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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3.
公开(公告)号:US20150110791A1
公开(公告)日:2015-04-23
申请号:US14283038
申请日:2014-05-20
Applicant: GENENTECH, INC.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S. Dennis , James A. Ernst , Ryan J. Watts , Gregory A. Lazar
IPC: C07K16/28 , A61K39/395 , A61K45/06 , A61K47/48
CPC classification number: C07K16/2881 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/40 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
Abstract translation: 本发明涉及抗转铁蛋白受体抗体及其使用方法。
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公开(公告)号:US11098129B2
公开(公告)日:2021-08-24
申请号:US16670104
申请日:2019-10-31
Applicant: Genentech, Inc.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S Dennis , James A Ernst , Ryan J Watts , Gregory A Lazar
IPC: C07K16/28 , C07K16/40 , A61K39/395 , A61K39/00
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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公开(公告)号:US10508151B2
公开(公告)日:2019-12-17
申请号:US15525832
申请日:2015-11-18
Applicant: Genentech, Inc.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S Dennis , James A Ernst , Ryan J Watts , Gregory A Lazar
IPC: C07K16/28 , C07K16/40 , A61K39/395 , A61K39/00
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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公开(公告)号:US20180134797A1
公开(公告)日:2018-05-17
申请号:US15525832
申请日:2015-11-18
Applicant: Genentech, Inc.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S Dennis , James A Ernst , Ryan J Watts , Gregory A Lazar
IPC: C07K16/28 , C07K16/40 , A61K39/395
CPC classification number: C07K16/2881 , A61K39/39558 , A61K2039/505 , C07K16/283 , C07K16/40 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/90 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-trans-ferrin receptor antibodies and methods of their use.
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7.METHODS FOR IMPROVING SAFETY OF BLOOD-BRAIN BARRIER TRANSPORT 审中-公开
Title translation: 改善血液屏障运输安全的方法公开(公告)号:US20150353639A1
公开(公告)日:2015-12-10
申请号:US14761895
申请日:2013-05-20
Applicant: Genentech, Inc.
Inventor: Ryan Jefferson Watts , Joy Yu Zuchero , Jessica Couch , Mark Dennis
CPC classification number: A61K39/3955 , A61K35/18 , A61K39/39583 , A61K47/6849 , A61K47/6879 , A61K2039/505 , A61K2039/545 , C07K16/2881 , C07K16/40 , C07K16/44 , C07K16/468 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/52 , C07K2317/71 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C07K2319/30
Abstract: The present disclosure relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport.
Abstract translation: 本公开涉及用于改善血脑屏障受体介导的血脑屏障转运的安全性的组合物和方法。
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公开(公告)号:US11167038B2
公开(公告)日:2021-11-09
申请号:US16033489
申请日:2018-07-12
Applicant: Genentech, Inc.
Inventor: Ryan Jefferson Watts , Joy Yu Zuchero , Jessica Couch , Mark Dennis
Abstract: The present invention relates to compositions and methods for improving the safety of blood-brain barrier receptor-mediated blood-brain barrier transport.
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公开(公告)号:US11008403B2
公开(公告)日:2021-05-18
申请号:US15525821
申请日:2015-11-18
Applicant: Genentech, Inc. , Adimab LLC
Inventor: Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus , Yin Zhang , Joy Yu Zuchero , Jessica Couch , Mark S Dennis , James A Ernst , Gregory A Lazar
Abstract: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
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公开(公告)号:US10808036B2
公开(公告)日:2020-10-20
申请号:US15614149
申请日:2017-06-05
Applicant: Genentech, Inc.
Inventor: Yin Zhang , Joy Yu Zuchero , Jasvinder Atwal , Jessica Couch , Mark S. Dennis , James A. Ernst , Ryan J. Watts , Gregory A. Lazar
Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
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