公开(公告)号：US20240067752A1

公开(公告)日：2024-02-29

申请号：US18474445

申请日：2023-09-26

Applicant: Genentech, Inc.

Inventor： Robert F. KELLEY ,  Daniel K. KIRCHHOFER ,  Joyce LAI ,  Chingwei V. LEE ,  Wei-Ching LIANG ,  Michael T. LIPARI ,  Kelly M. LOYET ,  Tao SAI ,  Menno VAN LOOKEREN CAMPAGNE ,  Yan WU ,  Germaine FUH

IPC: C07K16/40 ,  A61K39/395

CPC classification number: C07K16/40 ,  A61K39/3955 ,  A61K2039/507 ,  C07K2317/24 ,  C07K2317/34 ,  C07K2317/53 ,  C07K2317/55 ,  C07K2317/92 ,  C07K2317/94

Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.

公开(公告)号：US20170145113A1

公开(公告)日：2017-05-25

申请号：US15336171

申请日：2016-10-27

Applicant: Genentech, Inc.

Inventor： Robert F. KELLEY ,  Daniel K. KIRCHHOFER ,  Joyce LAI ,  Chingwei V. LEE ,  Wei-Ching LIANG ,  Michael T. LIPARI ,  Kelly M. LOYET ,  Tao SAI ,  Menno VAN LOOKEREN CAMPAGNE ,  Yan WU ,  Germaine FUH

IPC: C07K16/40

Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.