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公开(公告)号:US20230279102A1
公开(公告)日:2023-09-07
申请号:US18062956
申请日:2022-12-07
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , C07K16/30 , A61K45/06 , A61K39/395
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , A61K2039/507 , C07K2317/34 , C07K2317/56 , C07K2317/90 , C07K2317/94
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20130129743A1
公开(公告)日:2013-05-23
申请号:US13651289
申请日:2012-10-12
Applicant: GENENTECH, INC.
Inventor: Yan WU , Menno van LOOKEREN-CAMPAGNE , Daniel KIRCHHOFER , Michael Terry LIPARI , Kenneth J. KATSCHKE, JR. , Paul M. MORAN , Scott STAWICKI , Wei-Ching LIANG
IPC: C07K16/40
CPC classification number: C07K16/40 , C07K2317/34 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-HtrA1 antibodies and methods of using the same.
Abstract translation: 本发明提供抗HtrA1抗体及其使用方法。
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公开(公告)号:US20240117037A1
公开(公告)日:2024-04-11
申请号:US18345587
申请日:2023-06-30
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , A61K39/395 , A61K45/06 , C07K16/30
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , A61K2039/507 , C07K2317/56 , C07K2317/567 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20240003900A1
公开(公告)日:2024-01-04
申请号:US18174889
申请日:2023-02-27
Applicant: Genentech, Inc.
Inventor: Wei-Ching LIANG , WeiYu LIN , Yan WU
CPC classification number: G01N33/6854 , C07K16/2803 , C07K2317/92 , C07K2317/565 , G01N33/54326
Abstract: Provided herein are methods for the production and identification of antibodies that bind to a desired region of a target protein.
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公开(公告)号:US20170088613A1
公开(公告)日:2017-03-30
申请号:US15274603
申请日:2016-09-23
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , A61K45/06 , C07K16/30 , A61K39/395
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20220135701A1
公开(公告)日:2022-05-05
申请号:US17500741
申请日:2021-10-13
Applicant: Genentech, Inc.
Inventor: Wei-Ching LIANG , WeiYu Lin , Yan Wu , Minhong Yan
Abstract: The present disclosure provides anti-MerTK antibodies and methods of use thereof. The methods comprise administering an anti-MerTK antibody or an immunoconjugate thereof.
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公开(公告)号:US20220064286A1
公开(公告)日:2022-03-03
申请号:US17526338
申请日:2021-11-15
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20210301005A1
公开(公告)日:2021-09-30
申请号:US17205663
申请日:2021-03-18
Applicant: Genentech, Inc.
Inventor: Wei-Ching LIANG , Joseph R. ARRON , Daryle DEPIANTO , Wendy Green HALPERN , WeiYu LIN , Patrick J. LUPARDUS , Thirumalai Rajan RAMALINGAM , Dhaya SESHASAYEE , Tianhe SUN , Tulika TYAGI , Jia WU , Yan WU , Jian Ping YIN
Abstract: The invention provides isoform-selective anti-TGFβ antibodies and methods of using the same. In particular, isoform-selective anti-TGFβ2, anti-TGFβ3, and anti-TGFβ2/3 monoclonal antibodies are provided, e.g., for the treatment of fibrosis and other TGFβ-related disorders.
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公开(公告)号:US20150366989A1
公开(公告)日:2015-12-24
申请号:US14789873
申请日:2015-07-01
Applicant: GENENTECH, INC.
Inventor: Wei-Ching LIANG , Chie SAKANAKA , Yan WU
CPC classification number: A61K47/48638 , A61K47/6811 , A61K47/6851 , A61K47/6889 , A61K51/1045 , A61K2039/505 , C07K16/005 , C07K16/30 , C07K16/3069 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , C12N9/96
Abstract: Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided.
Abstract translation: 提供抗TAT226抗体及其免疫偶联物。 提供了使用抗TAT226抗体及其免疫偶联物的方法。
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公开(公告)号:US20190119376A1
公开(公告)日:2019-04-25
申请号:US15994583
申请日:2018-05-31
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K45/06 , A61K38/17 , C07K16/30 , A61K39/395
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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