公开(公告)号：US20160346181A1

公开(公告)日：2016-12-01

申请号：US15235587

申请日：2016-08-12

Applicant: Givaudan SA

Inventor： Andreas NATSCH ,  Michael WASESCHA

IPC: A61K8/40 ,  A61K8/37 ,  A61Q19/00 ,  A61K8/35 ,  A61Q13/00 ,  A61K8/368 ,  A61K8/33

CPC classification number: A61K8/40 ,  A61K8/33 ,  A61K8/347 ,  A61K8/35 ,  A61K8/368 ,  A61K8/37 ,  A61K31/05 ,  A61K31/275 ,  A61K2800/75 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q19/00

Abstract: The invention relates to organic compounds having the ability to reduce or suppress the onset of skin irritation induced by extraneous cause selected from the group of 2-heptylcyclopentanone, 2-ethoxynaphthalene; 2-methoxynaphthalene; 1-methoxy-4-(prop-1-enyl)benzene; 1-(cyclopropylmethyl)-4-methoxybenzene; wherein X, Y, and R1 to R11 have the same meaning as given in the description. Furthermore the invention refers to compositions for topical application to the skin comprising them. It further relates to a method of reducing or suppressing the formation of skin irritation.

Abstract translation: 此外，本发明涉及用于局部施用于包含它们的皮肤的组合物。 本发明还涉及减少或抑制皮肤刺激形成的方法。