公开(公告)号：US20190023643A1

公开(公告)日：2019-01-24

申请号：US16071739

申请日：2017-02-15

Applicant: GIVAUDAN SA

Inventor： Andreas Goeke ,  Felix FLACHSMANN ,  Dominique LELIEVRE ,  Andreas NATSCH ,  Francis VOIROL ,  Yue ZOU

IPC: C07C69/608 ,  C07C229/04 ,  C07C323/52 ,  A61Q13/00

CPC classification number: C07C69/608 ,  A61K8/37 ,  A61K8/46 ,  A61Q13/00 ,  C07C69/533 ,  C07C69/56 ,  C07C229/04 ,  C07C323/52 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/16

Abstract: A compound of formula I wherein R1, R2, R3 and R4 can be independently selected from H or Me, n=0, 1, the dotted lines are indicating single bonds, or in case n=0 an isolated double bond at position 3′, or in case n=1 an isolated double bond at position 3′ or 4′, and the wavy bond is indicating an unspecified configuration of the adjacent double bond. Said compounds, as well as precursors capable to generate said compounds, are useful as fragrance ingredients.

公开(公告)号：US20240132487A1

公开(公告)日：2024-04-25

申请号：US17769198

申请日：2020-10-15

Applicant: Givaudan SA

Inventor： Nicolas COCITO ARMANINO ,  Agnes BOMBRUN ,  An CHAI ,  Julie CHARPENTIER ,  Chun CHEN ,  Roger EMTER ,  Marion MATHYS ,  Andreas NATSCH ,  Chao WANG ,  Lijun ZHOU

IPC: C07D417/14 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14

CPC classification number: C07D417/14 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07B2200/07 ,  C07B2200/09

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.

公开(公告)号：US20230098332A1

公开(公告)日：2023-03-30

申请号：US17800049

申请日：2021-03-04

Applicant: Givaudan SA

Inventor： Nicolas COCITO ARMANINO ,  Julie CHARPENTIER ,  Chun CHEN ,  Changming DING ,  Roger EMTER ,  Andreas NATSCH ,  Chao WANG ,  Lijun ZHOU

IPC: C07D295/096 ,  C07D309/04 ,  C07D335/02 ,  C07D279/12 ,  C07D241/04

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucosa.

公开(公告)号：US20190062671A1

公开(公告)日：2019-02-28

申请号：US16078448

申请日：2017-03-15

Applicant: Givaudan SA

Inventor： Andreas NATSCH ,  Dominique LELIEVRE

IPC: C11B9/00

Abstract: A fragrance suitable as a substitute for Citral (3,7-dimethyl-2,6-octadienal) and fragranced products, essentially free of Citral but reminiscent of the odor and performance of Citral nevertheless.

公开(公告)号：US20240426807A1

公开(公告)日：2024-12-26

申请号：US18570418

申请日：2022-06-21

Applicant: Givaudan SA

Inventor： Roger EMTER ,  Andreas NATSCH

IPC: G01N33/50 ,  C12N9/22 ,  C12N15/11 ,  C12N15/90

Abstract: Described herein are nucleic acid constructs comprising a promoter and/or enhancer sequence operably linked to a nucleic acid sequence encoding a polypeptide, wherein said promoter and/or enhancer is inducible by an olfactory receptor, cells and populations comprising said constructs, and methods for expressing olfactory receptors and for identifying novel olfactory receptors and receptor-ligand interactions.

公开(公告)号：US20230002334A1

公开(公告)日：2023-01-05

申请号：US17777910

申请日：2020-11-26

Applicant: Givaudan SA

Inventor： Chao WANG ,  Nicolas COCITO ARMANINO ,  Julie CHARPENTIER ,  Chun CHEN ,  Roger EMTER ,  Andreas GOEKE ,  Feng HUANG ,  Andreas NATSCH ,  Lijun ZHOU ,  Yue ZOU

IPC: C07D265/16 ,  C07D498/04 ,  A61Q19/00 ,  A61Q11/02

Abstract: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.

公开(公告)号：US20180230399A1

公开(公告)日：2018-08-16

申请号：US15516238

申请日：2014-11-10

Applicant: GIVAUDAN SA

Inventor： Andreas GOEKE ,  Helke LAUE ,  Andreas NATSCH ,  Francis VOIROL

IPC: C11B9/00 ,  C07C47/228 ,  C11D3/50 ,  C11D3/20

Abstract: The use of a compound represented by the formula I wherein R1 through R4 is independently H or methyl; and R5 is a branched or linear, saturated or unsaturated C3-C7 alkyl, alkenyl, cycloalkyl or cycloalkenyl residue, as perfume ingredients in personal care and household care products.

公开(公告)号：US20240173230A1

公开(公告)日：2024-05-30

申请号：US18549200

申请日：2022-04-08

Applicant: GIVAUDAN SA

Inventor： Stephen David WATKINS ,  Andreas NATSCH ,  Anne-Cecile KRALKA

IPC: A61K8/37 ,  A61K8/31 ,  A61K8/33 ,  A61K8/34 ,  A61K8/35 ,  A61K8/49 ,  A61K8/58 ,  A61K8/9789 ,  A61K8/99 ,  A61Q15/00

CPC classification number: A61K8/37 ,  A61K8/31 ,  A61K8/33 ,  A61K8/34 ,  A61K8/342 ,  A61K8/35 ,  A61K8/4973 ,  A61K8/498 ,  A61K8/58 ,  A61K8/9789 ,  A61K8/99 ,  A61Q15/00 ,  A61K2800/77

Abstract: The present disclosure provides microbiome-friendly fragrance compositions adapted to mask, reduce or prevent malodours and consumer products comprising such a microbiome-friendly fragrance composition.

公开(公告)号：US20160346181A1

公开(公告)日：2016-12-01

申请号：US15235587

申请日：2016-08-12

Applicant: Givaudan SA

Inventor： Andreas NATSCH ,  Michael WASESCHA

IPC: A61K8/40 ,  A61K8/37 ,  A61Q19/00 ,  A61K8/35 ,  A61Q13/00 ,  A61K8/368 ,  A61K8/33

CPC classification number: A61K8/40 ,  A61K8/33 ,  A61K8/347 ,  A61K8/35 ,  A61K8/368 ,  A61K8/37 ,  A61K31/05 ,  A61K31/275 ,  A61K2800/75 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q19/00

Abstract: The invention relates to organic compounds having the ability to reduce or suppress the onset of skin irritation induced by extraneous cause selected from the group of 2-heptylcyclopentanone, 2-ethoxynaphthalene; 2-methoxynaphthalene; 1-methoxy-4-(prop-1-enyl)benzene; 1-(cyclopropylmethyl)-4-methoxybenzene; wherein X, Y, and R1 to R11 have the same meaning as given in the description. Furthermore the invention refers to compositions for topical application to the skin comprising them. It further relates to a method of reducing or suppressing the formation of skin irritation.

Abstract translation: 此外，本发明涉及用于局部施用于包含它们的皮肤的组合物。 本发明还涉及减少或抑制皮肤刺激形成的方法。