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公开(公告)号：US07039462B2
公开(公告)日：2006-05-02
申请号：US10172825
申请日：2002-06-14
申请人： Joseph M. Pastore , Rodney W. Salo , Quan Ni , Qingsheng Zhu , Jiang Ding
发明人： Joseph M. Pastore , Rodney W. Salo , Quan Ni , Qingsheng Zhu , Jiang Ding
CPC分类号： A61N1/3925 , A61N1/3627 , A61N1/365 , A61N1/36514 , A61N1/36521 , A61N1/36542
摘要： A cardiac rhythm management device is configured to detect mechanical oscillations in cardiac rhythm. Upon detection of such oscillations, the device may adjust its operating behavior to compensate for the deleterious effects of the condition.
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2.发明授权公开(公告)号：US08805503B2
公开(公告)日：2014-08-12
申请号：US12699457
申请日：2010-02-03
申请人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
发明人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
IPC分类号： A61N1/362
CPC分类号： A61N1/36592 , A61B5/02405 , A61B5/4035 , A61N1/36114 , A61N1/368
摘要： A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used to evaluate a plurality of parameter values for selecting an approximately optimal parameter value.
摘要翻译： 心律管理系统基于心率变异性（HRV）调节起搏和/或自主神经刺激脉冲的传递。 产生作为HRV的量度的HRV参数以指示患者的心脏状况，基于该HRV参数开始，停止，调整或优化起搏和/或自主神经刺激脉冲的递送。 在一个实施例中，HRV参数用于评估用于选择近似最佳参数值的多个参数值。
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3.发明申请METHOD AND APPARATUS FOR USING HEART RATE VARIABILITY AS A SAFETY CHECK IN ELECTRICAL THERAPIES 有权使用心率变化作为安全检查在电疗中的方法和装置公开(公告)号：US20100131026A1
公开(公告)日：2010-05-27
申请号：US12694124
申请日：2010-01-26
申请人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
发明人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
IPC分类号： A61N1/365
CPC分类号： A61N1/365 , A61N1/36592
摘要： A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used as a safety check to stop an electrical therapy when it is believed to be potentially harmful to continue the therapy.
摘要翻译： 心律管理系统基于心率变异性（HRV）调节起搏和/或自主神经刺激脉冲的传递。 产生作为HRV的量度的HRV参数以指示患者的心脏状况，基于该HRV参数开始，停止，调整或优化起搏和/或自主神经刺激脉冲的递送。 在一个实施例中，当HRV参数被认为对继续治疗有潜在危害时，将HRV参数用作安全检查以停止电疗法。
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4.发明申请公开(公告)号：US20100137932A1
公开(公告)日：2010-06-03
申请号：US12699457
申请日：2010-02-03
申请人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
发明人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
CPC分类号： A61N1/36592 , A61B5/02405 , A61B5/4035 , A61N1/36114 , A61N1/368
摘要： A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used to evaluate a plurality of parameter values for selecting an approximately optimal parameter value.
摘要翻译： 心律管理系统基于心率变异性（HRV）调节起搏和/或自主神经刺激脉冲的传递。 产生作为HRV的量度的HRV参数以指示患者的心脏状况，基于该HRV参数开始，停止，调整或优化起搏和/或自主神经刺激脉冲的递送。 在一个实施例中，HRV参数用于评估用于选择近似最佳参数值的多个参数值。
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5.发明授权Method and apparatus for using heart rate variability as a safety check in electrical therapies 失效使用心率变异性作为电疗法安全检查的方法和装置公开(公告)号：US07672725B2
公开(公告)日：2010-03-02
申请号：US11037309
申请日：2005-01-18
申请人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
发明人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
IPC分类号： A61N1/362
CPC分类号： A61N1/365 , A61N1/36592
摘要： A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used as a safety check to stop an electrical therapy when it is believed to be potentially harmful to continue the therapy.
摘要翻译： 心律管理系统基于心率变异性（HRV）调节起搏和/或自主神经刺激脉冲的传递。 产生作为HRV的量度的HRV参数以指示患者的心脏状况，基于该HRV参数开始，停止，调整或优化起搏和/或自主神经刺激脉冲的递送。 在一个实施例中，当HRV参数被认为对继续治疗有潜在危害时，将HRV参数用作安全检查以停止电疗法。
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6.发明授权公开(公告)号：US07672724B2
公开(公告)日：2010-03-02
申请号：US11037308
申请日：2005-01-18
申请人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
发明人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
IPC分类号： A61N1/362
CPC分类号： A61N1/36592 , A61B5/02405 , A61B5/4035 , A61N1/36114 , A61N1/368
摘要： A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used to evaluate a plurality of parameter values for selecting an approximately optimal parameter value.
摘要翻译： 心律管理系统基于心率变异性（HRV）调节起搏和/或自主神经刺激脉冲的传递。 产生作为HRV的量度的HRV参数以指示患者的心脏状况，基于该HRV参数开始，停止，调整或优化起搏和/或自主神经刺激脉冲的递送。 在一个实施例中，HRV参数用于评估用于选择近似最佳参数值的多个参数值。
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7.发明授权Method and apparatus for using heart rate variability to control maximum tracking rate in pacing therapy 有权心率变异性控制起搏治疗最大跟踪率的方法和装置公开(公告)号：US07580745B2
公开(公告)日：2009-08-25
申请号：US11037723
申请日：2005-01-18
申请人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
发明人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
IPC分类号： A61N1/365
CPC分类号： A61B5/02405 , A61B5/4035 , A61N1/36114 , A61N1/36592 , A61N1/368
摘要： A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used to adjust a maximum tracking rate in an atrial tracking pacing mode.
摘要翻译： 心律管理系统基于心率变异性（HRV）调节起搏和/或自主神经刺激脉冲的传递。 产生作为HRV的量度的HRV参数以指示患者的心脏状况，基于该HRV参数开始，停止，调整或优化起搏和/或自主神经刺激脉冲的递送。 在一个实施例中，HRV参数用于调整心房跟踪起搏模式中的最大跟踪率。
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8.发明授权Method and apparatus for using heart rate variability as a safety check in electrical therapies 有权使用心率变异性作为电疗法安全检查的方法和装置公开(公告)号：US08831724B2
公开(公告)日：2014-09-09
申请号：US12694124
申请日：2010-01-26
申请人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
发明人： Joseph M. Pastore , Rodney W. Salo , Gerrard M. Carlson , Andrew P. Kramer , Jiang Ding , Yinghong Yu
CPC分类号： A61N1/365 , A61N1/36592
摘要： A cardiac rhythm management system modulates the delivery of pacing and/or autonomic neurostimulation pulses based on heart rate variability (HRV). An HRV parameter being a measure of the HRV is produced to indicate a patient's cardiac condition, based on which the delivery of pacing and/or autonomic neurostimulation pulses is started, stopped, adjusted, or optimized. In one embodiment, the HRV parameter is used as a safety check to stop an electrical therapy when it is believed to be potentially harmful to continue the therapy.
摘要翻译： 心律管理系统基于心率变异性（HRV）调节起搏和/或自主神经刺激脉冲的传递。 产生作为HRV的量度的HRV参数以指示患者的心脏状况，基于该HRV参数开始，停止，调整或优化起搏和/或自主神经刺激脉冲的递送。 在一个实施例中，当HRV参数被认为对继续治疗有潜在危害时，将HRV参数用作安全检查以停止电疗法。
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9.发明授权公开(公告)号：US07881789B2
公开(公告)日：2011-02-01
申请号：US11832552
申请日：2007-08-01
IPC分类号： A61N1/368
CPC分类号： A61N1/3622 , A61N1/3627 , A61N1/3684
摘要： A cardiac rhythm management device is configured to detect oscillations in cardiac rhythm by comparing electrogram signals during successive heart beats. Upon detection of electrical alternans, the device may adjust its operating behavior to compensate for the deleterious effects of the condition.
摘要翻译： 心律管理装置被配置为通过在连续的心搏期间比较电描记图信号来检测心律的振动。 在检测到电气交流电时，该装置可以调整其操作行为以补偿该状况的有害影响。
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10.发明授权公开(公告)号：US07257443B2
公开(公告)日：2007-08-14
申请号：US11184325
申请日：2005-07-19
IPC分类号： A61N1/368
CPC分类号： A61N1/3622 , A61N1/3627 , A61N1/3684
摘要： A cardiac rhythm management device is configured to detect oscillations in cardiac rhythm by comparing electrogram signals during successive heart beats. Upon detection of electrical alternans, the device may adjust its operating behavior to compensate for the deleterious effects of the condition.
摘要翻译： 心律管理装置被配置为通过在连续的心搏期间比较电描记图信号来检测心律的振动。 在检测到电气交流电时，该装置可以调整其操作行为以补偿该状况的有害影响。
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