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公开(公告)号:US20070167608A1
公开(公告)日:2007-07-19
申请号:US10596704
申请日:2004-06-30
申请人: Jun Hirabayashi , Atsushi Kuno , Sachiko Nakamura , Noboru Uchiyama , Ken-ichi Kasai , Yoichiro Arata , Yoriko Takahashi
发明人: Jun Hirabayashi , Atsushi Kuno , Sachiko Nakamura , Noboru Uchiyama , Ken-ichi Kasai , Yoichiro Arata , Yoriko Takahashi
IPC分类号: C07K14/00
CPC分类号: G01N33/543 , G01N30/02 , G01N30/8679 , G01N33/54366 , G01N2030/8813 , B01D15/428
摘要: The present inventors discovered that lectins recognize extremely small differences in sugar chain structures, and that by using this ability to recognize sugar chain structures, numerous sugar chain structures can be distinguished using the strong or weak interaction patterns of about ten types of lectins. Therefore, by reference to and use of control interaction data, in which large amounts of data on the interactions between sugar chains and lectins have been collected, the structures of subject sugar chains can be identified, estimated, and such with high accuracy.
摘要翻译: 本发明人发现,凝集素识别糖链结构的极小差异,并且通过使用这种能力来识别糖链结构,许多糖链结构可以使用约10种凝集素的强或弱相互作用模式进行区分。 因此,通过参考和使用控制相互作用数据,其中收集了大量关于糖链和凝集素之间的相互作用的数据,可以高精度地鉴定,估计主题糖链的结构。