公开(公告)号：US09265806B2

公开(公告)日：2016-02-23

申请号：US14038378

申请日：2013-09-26

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH (CSIR)

Inventor： Hyun Ok Yang ,  Sung-Kwon Chung ,  Hak Cheol Kwon ,  Jin Wook Cha ,  Vinesh Jaichand Maharaj ,  Rudzani Nthambeleni ,  Dashnie Naidoo ,  Young-Joo Kim ,  Jungyeob Ham ,  Jeremiah Senabe ,  Gerda Fouche ,  Eric Khorombi ,  Joon Ki Kim

IPC: A01N65/00 ,  A61K36/185 ,  A23L1/30 ,  A23L2/52

CPC classification number: A61K36/185 ,  A23L2/52 ,  A23L33/105 ,  A61K2236/39

Abstract: A pharmaceutical composition and a food composition including extracts of Monsonia sp. for treating dementia, which compositions inhibit the formation of β-amyloid, and a method of preparing the extracts.

Abstract translation: 一种药物组合物和包含Monsonia sp。 用于治疗痴呆，所述组合物抑制β-淀粉样蛋白的形成，以及制备提取物的方法。

公开(公告)号：US20140088186A1

公开(公告)日：2014-03-27

申请号：US14036810

申请日：2013-09-25

Applicant: The Council for Scientific and Industrial Research ,  KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyun Ok Yang ,  Sung-Kwon Chung ,  Hak Cheol Kwon ,  Jin Wook Cha ,  Young-Joo Kim ,  Gerda Fouche ,  Rudzani Nthambeleni ,  Dashnie Naidoo ,  Jeremiah Senabe ,  Vinesh Jaichand Maharaj ,  Eric Khorombi ,  Jungyeob Ham ,  Joon Ki Kim

IPC: A61K31/365 ,  A23L2/52 ,  A23L1/30

CPC classification number: A61K31/365 ,  A23L2/52 ,  A23L33/105 ,  A61K36/185

Abstract: A composition for preventing and/or treating dementia and ameliorating memory impairment and/or improving memory, comprising one or more arylnaphthalene lignan derivatives, such as Justicidin A, 5-methoxyjusticidin A, Chinensinaphthol, and a pharmaceutically-acceptable salt thereof, as active ingredient.

Abstract translation: 包含一种或多种芳基萘木酚素衍生物，例如贾斯汀素A，5-甲氧基调节蛋白A，钦嗪萘酚及其药学上可接受的盐作为活性成分的用于预防和/或治疗痴呆并改善记忆障碍和/或改善记忆的组合物 。

公开(公告)号：US09211278B2

公开(公告)日：2015-12-15

申请号：US14036810

申请日：2013-09-25

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  The Council for Scientific and Industrial Research

Inventor： Hyun Ok Yang ,  Sung-Kwon Chung ,  Hak Cheol Kwon ,  Jin Wook Cha ,  Young-Joo Kim ,  Gerda Fouche ,  Rudzani Nthambeleni ,  Dashnie Naidoo ,  Jeremiah Senabe ,  Vinesh Jaichand Maharaj ,  Eric Khorombi ,  Jungyeob Ham ,  Joon Ki Kim

IPC: A01N43/30 ,  A61K31/36 ,  A61K31/365 ,  A23L1/30 ,  A23L2/52 ,  A61K36/185

CPC classification number: A61K31/365 ,  A23L2/52 ,  A23L33/105 ,  A61K36/185

Abstract: Composition and method for preventing and/or treating dementia and ameliorating memory impairment and/or improving memory, comprising one or more arylnaphthalene lignan derivatives, namely Justicidin A, 5-methoxyjusticidin A, Chinensinaphthol, and a pharmaceutically-acceptable salt thereof, as active ingredient.

Abstract translation: 包含一种或多种芳基萘木酚素衍生物的组合物和方法，其中包括一种或多种芳基萘木酚素衍生物，即Justicidin A，5-甲氧基调节蛋白A，Chinininaphthol及其药学上可接受的盐作为活性成分 。

公开(公告)号：US09132160B2

公开(公告)日：2015-09-15

申请号：US13661205

申请日：2012-10-26

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyun Ok Yang ,  Hak Cheol Kwon ,  Joon Ki Kim ,  Jin Wook Cha ,  Young-Joo Kim ,  Jungyeob Ham

IPC: A61K36/00 ,  A61K36/489

CPC classification number: A61K36/489 ,  A23L33/105 ,  A23V2002/00 ,  A61K2236/30 ,  A23V2200/334 ,  A23V2250/21

Abstract: A method of preventing or alleviating alcohol hangover, which comprises administering one or more selected from the group consisting of Sophora flavescens extracts, dried products of the extracts, and concentrates of the extracts to a subject in need of preventing or alleviating alcohol hangover is provided.

Abstract translation: 提供了一种预防或减轻酒精宿醉的方法，其包括将需要预防或缓解酒精宿醉的受试者中的一种或多种选自由苦参提取物，提取物的干燥产物和提取物的浓缩物组成的组。