公开(公告)号：US10653732B2

公开(公告)日：2020-05-19

申请号：US15935634

申请日：2018-03-26

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jungyeob Ham ,  Bong Chul Chung ,  Taejung Kim ,  Pilju Choi ,  Ki Sung Kang ,  Buyng Su Hwang ,  Kyu Sun Kim

IPC: A61K36/062 ,  A61P3/10 ,  A61K31/122 ,  A23L33/10 ,  A61K31/05 ,  C07C35/44 ,  C07C39/205 ,  C07C39/14

Abstract: Provided are a composition for stimulating insulin secretion from cells, the composition including a Hypoxylon truncatum extract or an active ingredient thereof, and a method of stimulating insulin secretion from cells.

公开(公告)号：US20130178436A1

公开(公告)日：2013-07-11

申请号：US13737482

申请日：2013-01-09

Applicant: Korea Institute of Science and Technology

Inventor： Ki Sung Kang ,  Su-Nam Kim, I ,  Jungyeob Ham ,  Woojung Lee ,  Noriko Yamabe ,  Ji Hwan Lee

IPC: A61K31/704

CPC classification number: A61K31/704 ,  A23L33/105 ,  A61K9/0095 ,  A61K9/1623 ,  A61K9/1664 ,  A61K9/2018 ,  A61K9/2059 ,  A61K9/4858 ,  A61K9/4866

Abstract: A composition for preventing, improving, or treating renal diseases, the composition including as an active ingredient a Maillard browning reaction product obtained by reacting ginsenoside Re, an extract of Panax species plant including ginsenoside Re, or glucose with amino acid at a temperature of 100 to 130° C. for 0.5 to 12 hours.

Abstract translation: 用于预防，改善或治疗肾脏疾病的组合物，所述组合物包含作为活性成分的美拉德褐变反应产物，其通过使人参皂甙Re，人参皂甙Re的人参提取物或葡萄糖与氨基酸在100℃的温度下反应而获得 至130℃，保持0.5至12小时。