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    METHOD OF PREPARING SELF-ASSEMBLED EXTRACELLULAR MATRICES AND USE OF SELF-ASSEMBLED EXTRACELLULAR MATRICES FORMED BY USING THE METHOD
    1.
    发明申请
    METHOD OF PREPARING SELF-ASSEMBLED EXTRACELLULAR MATRICES AND USE OF SELF-ASSEMBLED EXTRACELLULAR MATRICES FORMED BY USING THE METHOD 审中-公开
    制备自组装细胞外基质的方法和使用方法制备的自组装细胞外基质的方法

    公开(公告)号：US20130101635A1

    公开(公告)日：2013-04-25

    申请号：US13650670

    申请日：2012-10-12

    申请人： Kwideok PARK ,  Soon Eon BAE ,  Dong Keun HAN

    发明人： Kwideok PARK ,  Soon Eon BAE ,  Dong Keun HAN

    IPC分类号： C12N5/00 ,  A61K35/32 ,  A61K35/28

    CPC分类号： C12N5/0062 ,  A61K35/28 ,  A61K35/32 ,  C12N2533/90

    摘要： Methods of preparing a self-assembled matrix from cell-derived extracellular matrice, and of inducing cell proliferation and differentiation by using the self-assembled matrix, and applying the self-assembled matrix into cell therapy. In detail, unique extracellular matrices obtained from particular cells are collected and then subjected to decellularization in order to form a self-assembled matrix including nano fibers only formed of extracellular matrix. In addition, the matrix prepared as described above provides a platform that is effective for the induction of the mass proliferation or differentiation of cells, and thus, may be applied in manufacturing cell therapy products.

    摘要翻译： 从细胞衍生的细胞外基质制备自组装基质的方法，以及通过使用自组装基质诱导细胞增殖和分化，以及将自组装基质应用于细胞治疗。 详细地，从特定细胞获得的独特的细胞外基质被收集，然后进行脱细胞化以形成仅由细胞外基质形成的纳米纤维的自组装基质。 此外，如上所述制备的基质提供了对诱导细胞的大量增殖或分化有效的平台，因此可以应用于制造细胞治疗产品。