公开(公告)号：US09645153B2

公开(公告)日：2017-05-09

申请号：US14829346

申请日：2015-08-18

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Evan Antoulinakis ,  Kyle Gee ,  Aleksey Rukavishnikov

IPC: G01N33/58 ,  C07D311/18 ,  C07D495/22 ,  C07D493/14 ,  C07D209/18 ,  C07F5/02 ,  C09B11/26 ,  C09B45/00 ,  C07D311/82 ,  G01N33/532 ,  C07D401/10 ,  C07D209/14

CPC classification number: G01N33/58 ,  C07D209/14 ,  C07D209/18 ,  C07D311/18 ,  C07D311/82 ,  C07D401/10 ,  C07D493/14 ,  C07D495/22 ,  C07F5/022 ,  C09B11/24 ,  C09B11/26 ,  C09B23/04 ,  C09B23/08 ,  C09B45/00 ,  C09B56/16 ,  G01N33/532 ,  G01N33/582

Abstract: The present disclosure is directed to a reactive ester agent capable of conjugating a reporter molecule to a carrier molecule or solid support. The reactive ester agent has the general formula: wherein the variables are described throughout the application.

公开(公告)号：US09140706B2

公开(公告)日：2015-09-22

申请号：US13972081

申请日：2013-08-21

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Evan Antoulinakis ,  Kyle Gee ,  Aleksey Rukavishnikov

IPC: C07D311/80 ,  C07D311/82 ,  C07D311/88 ,  G01N33/58 ,  C07D209/14 ,  C07D401/10 ,  G01N33/532 ,  C09B11/26 ,  C09B45/00

CPC classification number: G01N33/58 ,  C07D209/14 ,  C07D209/18 ,  C07D311/18 ,  C07D311/82 ,  C07D401/10 ,  C07D493/14 ,  C07D495/22 ,  C07F5/022 ,  C09B11/24 ,  C09B11/26 ,  C09B23/04 ,  C09B23/08 ,  C09B45/00 ,  C09B56/16 ,  G01N33/532 ,  G01N33/582

Abstract: The present disclosure is directed to a reactive ester agent capable of conjugating a reporter molecule to a carrier molecule or solid support. The reactive ester agent has the general formula: wherein the variables are described throughout the application.

Abstract translation: 本公开涉及能够将报告分子与载体分子或固体支持物缀合的反应性酯试剂。 反应性酯剂具有以下通式：其中在整个申请中描述了变量。

公开(公告)号：US20130337536A1

公开(公告)日：2013-12-19

申请号：US13972081

申请日：2013-08-21

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Evan Antoulinakis ,  Kyle Gee ,  Aleksey Rukavishnikov

IPC: G01N33/58 ,  C09B11/26 ,  C09B45/00

CPC classification number: G01N33/58 ,  C07D209/14 ,  C07D209/18 ,  C07D311/18 ,  C07D311/82 ,  C07D401/10 ,  C07D493/14 ,  C07D495/22 ,  C07F5/022 ,  C09B11/24 ,  C09B11/26 ,  C09B23/04 ,  C09B23/08 ,  C09B45/00 ,  C09B56/16 ,  G01N33/532 ,  G01N33/582

Abstract: The present disclosure is directed to a reactive ester agent capable of conjugating a reporter molecule to a carrier molecule or solid support. The reactive ester agent has the general formula: wherein the variables are described throughout the application.