公开(公告)号：US20200333291A1

公开(公告)日：2020-10-22

申请号：US16922754

申请日：2020-07-07

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Ian WALTON ,  Robert COBENE ,  Alexander DUKHOVNY ,  Adam SANNICANDRO ,  John DIXON ,  Achim KARGER ,  Dan KLINE

IPC: G01N27/447 ,  G01N35/10

Abstract: In one aspect, a biological sequencing device comprising a cartridge configured to be removed from the instrument is disclosed. In various embodiments the cartridge can include one or more capillaries suitable for capillary electrophoresis, a reservoir and a pump. In various embodiments the reservoir can contain a separation matrix. In various embodiments the pump can load a capillary with separation matrix. In another aspect the biological sequencing device can include one or more capillaries and an integrated valve assembly. In various embodiments the integrated valve assembly can provide a polymer to the one or more capillaries.

公开(公告)号：US20200232943A1

公开(公告)日：2020-07-23

申请号：US16487795

申请日：2018-02-23

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Gary LIM ,  David LIU ,  Peng LI ,  Bin CAO ,  Kirk HIRANO ,  Alexander DUKHOVNY ,  John DIXON

IPC: G01N27/447

Abstract: A biological analysis device (100) for performing capillary electrophoresis includes a voltage section (124) configured to generate a voltage differential across a cathode (106) connector and an anode (116) connector, an optical detector system (112) configured to detect light emission from a sample, a temperature regulation section (126), and a cartridge holding portion configured to receive at least a portion of a removable cartridge (102) comprising one or more capillaries (104) and a separation medium container (118). The biological analysis device may include one or more actuators (122) configured to actuate components of the removable cartridge when the removable cartridge is received in the cartridge holding portion. Devices and methods relate to biological analysis.

公开(公告)号：US20220283118A1

公开(公告)日：2022-09-08

申请号：US17703859

申请日：2022-03-24

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Gary LIM ,  David LIU ,  Peng LI ,  Bin CAO ,  Kirk HIRANO ,  Alexander DUKHOVNY ,  John DIXON

IPC: G01N27/447

Abstract: A biological analysis device for performing capillary electrophoresis includes a voltage section configured to generate a voltage differential across a cathode connector and an anode connector, an optical detector system configured to detect light emission from a sample, a temperature regulation section, and a cartridge holding portion configured to receive at least a portion of a removable cartridge comprising one or more capillaries and a separation medium container. The biological analysis device may include one or more actuators configured to actuate components of the removable cartridge when the removable cartridge is received in the cartridge holding portion. Devices and methods relate to biological analysis.