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公开(公告)号:US20080131461A1
公开(公告)日:2008-06-05
申请号:US11665393
申请日:2005-10-13
申请人: Maria Grazia Pau , Jaap Goudsmit , Joseph D. Cohen , Patrice Dubois , V.Ann Stewart , Donald Heppner
发明人: Maria Grazia Pau , Jaap Goudsmit , Joseph D. Cohen , Patrice Dubois , V.Ann Stewart , Donald Heppner
CPC分类号: A61K39/015 , A61K2039/5256 , A61K2039/55572 , A61K2039/55577 , A61K2039/6075 , Y02A50/412
摘要: The invention relates to novel vaccine regimens in which specific prime/boost regimens are applied using low-neutralized recombinant adenoviral vectors harboring nucleic acids encoding antigens from Plasmodium falciparum and purified recombinant protein vaccines such as RTS,S, in the context of appropriate adjuvants.
摘要翻译: 本发明涉及新颖的疫苗方案,其中使用含有编码来自恶性疟原虫的抗原的核酸的低中和重组腺病毒载体和在合适佐剂的情况下使用纯化的重组蛋白疫苗如RTS,S应用特异性初始/加强方案。
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公开(公告)号:US20090285879A1
公开(公告)日:2009-11-19
申请号:US12317508
申请日:2008-12-23
申请人: Maria Grazia Pau , Jaap Goudsmit , Joseph D. Cohen , Patrice Dubois , V. Ann Stewart , Donald Heppner
发明人: Maria Grazia Pau , Jaap Goudsmit , Joseph D. Cohen , Patrice Dubois , V. Ann Stewart , Donald Heppner
IPC分类号: A61K9/127 , A61K39/235
CPC分类号: A61K39/015 , A61K2039/5256 , A61K2039/55572 , A61K2039/55577 , A61K2039/6075 , Y02A50/412
摘要: Described are vaccine regimens in which specific prime/boost regimens are applied using low-neutralized recombinant adenoviral vectors harboring nucleic acids encoding antigens from Plasmodium falciparum and purified recombinant protein vaccines such as RTS,S, in the context of appropriate adjuvants.
摘要翻译: 描述了在适当佐剂的情况下,使用含有编码来自恶性疟原虫的抗原的核酸的低中和重组腺病毒载体和诸如RTS,S的纯化的重组蛋白疫苗来应用特异性初始/加强方案的疫苗方案。
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