公开(公告)号：US20110125265A1

公开(公告)日：2011-05-26

申请号：US12950306

申请日：2010-11-19

Applicant: Charanpreet S. Bagga ,  Shaun B. Hanson ,  Christopher D. Mandeen ,  Michael J. Simpson ,  Steven B. Cohen ,  Charles F. Leinberry ,  Peter F. Sharkey

Inventor： Charanpreet S. Bagga ,  Shaun B. Hanson ,  Christopher D. Mandeen ,  Michael J. Simpson ,  Steven B. Cohen ,  Charles F. Leinberry ,  Peter F. Sharkey

IPC: A61F2/28

CPC classification number: A61F2/2846 ,  A61B17/68 ,  A61B17/7098 ,  A61B17/8615 ,  A61B17/863 ,  A61B17/864 ,  A61B17/8875 ,  A61B17/8897

Abstract: Devices and associated methods are disclosed for treating bone, and particularly bone tissue at the joints. Disclosed are implantable devices that can be used either alone or in combination with this augmentation or hardening material for the repair of bone defects and which are particularly suited for use at the joints, and even more particularly, suited for use at the subchondral bone level.

Abstract translation: 公开了用于治疗骨骼的装置和相关方法，特别是关节处的骨组织。 公开了可植入装置，其可单独使用或与该增强或硬化材料组合用于修复骨缺损，并且特别适合于在关节处使用，甚至更具体地适合于在软骨下骨水平使用。

公开(公告)号：US07944553B1

公开(公告)日：2011-05-17

申请号：US12702076

申请日：2010-02-08

Applicant: Michael J. Simpson ,  Jihong Xie

Inventor： Michael J. Simpson ,  Jihong Xie

IPC: G01B9/00

CPC classification number: G01M11/0292

Abstract: A method and system for measuring an optical property of a multi-focal lens are disclosed. One embodiment of the method comprises: filtering out light transmitted by all but one of a plurality of diffraction orders of the lens to provide an unfiltered light from a single diffraction order; receiving the unfiltered light at a wavefront detector; and analyzing the unfiltered light at the wavefront detector to measure the optical property. The multi-focal lens can be a multi-focal diffractive intra-ocular lens. The measured optical property can be a discontinuity in the lens surface. Filtering can comprise blocking all but the unfiltered light using an aperture operable to let through the unfiltered light from the single diffraction order, and/or blocking all but the unfiltered light using an opaque obstruction operable to let through only a selected amount of light corresponding to the light transmitted by the single diffraction order. The method can further comprise generating an image quality parameter, such as a modulation transfer function, based on the measured optical property.

Abstract translation: 公开了一种用于测量多焦点透镜的光学特性的方法和系统。 该方法的一个实施例包括：滤除由透镜的多个衍射级中的除了一个以外的全部透射的光以从单个衍射级提供未滤光的光; 在波前检测器处接收未过滤的光; 并分析波前检测器上的未过滤光以测量光学性质。 多焦点透镜可以是多焦点衍射眼内透镜。 所测量的光学特性可以是透镜表面的不连续性。 过滤可以包括使用可操作以通过来自单个衍射级的未过滤的光来进行的所有未过滤的光的遮挡，和/或使用不透明的遮挡物阻挡所有的未过滤的光，所述不透明遮挡可操作地仅通过选定量的对应于 光由单一的衍射顺序传输。 该方法还可以包括基于所测量的光学特性来生成诸如调制传递函数的图像质量参数。

公开(公告)号：US07777872B2

公开(公告)日：2010-08-17

申请号：US12181889

申请日：2008-07-29

Applicant: Michael J. Simpson

Inventor： Michael J. Simpson

IPC: G01B9/00

CPC classification number: G01M11/0228 ,  G01M11/0257 ,  G01M11/0292

Abstract: A method for measuring the optical properties of multifocal ophthalmic lenses. Collimated light is passed through an ophthalmic lens and onto an array of lenslets. Light exiting the array of lenslets is detected by a sensor. Blurred spots and/or double spots may represent diffractive zones of the wavefront. A centroid of the spot or a brighter of two spots may be used to determine the lateral position of the spot. Theoretical calculations, laboratory measurements, clinical measurements and experimental image spots may be generated, compared and cross-checked to determine a monofocal equivalent lens. A Modulation Transfer Function (MTF) may be used to evaluate and compare a diffractive lens and a monofocal equivalent lens.

Abstract translation: 一种用于测量多焦点眼科镜片的光学性质的方法。 准直光通过眼科镜片并穿过小镜片阵列。 通过传感器检测离开小透镜阵列的光。 模糊点和/或双点可以表示波前的衍射区。 斑点的质心或两个斑点的亮点可用于确定斑点的横向位置。 可以产生理论计算，实验室测量，临床测量和实验图像斑点，进行比较和交叉检查以确定单焦点等效透镜。 调制传递函数（MTF）可用于评估和比较衍射透镜和单焦点等效透镜。

公开(公告)号：US20090033920A1

公开(公告)日：2009-02-05

申请号：US12181889

申请日：2008-07-29

Applicant: Michael J. Simpson

Inventor： Michael J. Simpson

IPC: G01M11/02

CPC classification number: G01M11/0228 ,  G01M11/0257 ,  G01M11/0292

Abstract: A method for measuring the optical properties of multifocal ophthalmic lenses. Collimated light is passed through an ophthalmic lens and onto an array of lenslets. Light exiting the array of lenslets is detected by a sensor. Blurred spots and/or double spots may represent diffractive zones of the wavefront. A centroid of the spot or a brighter of two spots may be used to determine the lateral position of the spot. Theoretical calculations, laboratory measurements, clinical measurements and experimental image spots may be generated, compared and cross-checked to determine a monofocal equivalent lens. An MTF may be used to evaluate and compare a diffractive lens and a monofocal equivalent lens.

Abstract translation: 一种用于测量多焦点眼科镜片的光学性质的方法。 准直光通过眼科镜片并穿过小镜片阵列。 通过传感器检测离开小透镜阵列的光。 模糊点和/或双点可以表示波前的衍射区。 斑点的质心或两个斑点的亮点可用于确定斑点的横向位置。 可以产生理论计算，实验室测量，临床测量和实验图像斑点，进行比较和交叉检查以确定单焦点等效透镜。 可以使用MTF来评估和比较衍射透镜和单焦点等效透镜。

公开(公告)号：US20080269890A1

公开(公告)日：2008-10-30

申请号：US11742041

申请日：2007-04-30

Applicant: Michael J. Simpson ,  Xiaoxiao Zhang

Inventor： Michael J. Simpson ,  Xiaoxiao Zhang

IPC: A61F2/16

CPC classification number: A61F2/1613 ,  A61F2/1654

Abstract: In one aspect, the invention provides an intraocular lens (IOL) that includes an optic and a peripheral optical flange that surrounds the optic. The optic can form an image of a field of view on the IOL user's retina and the peripheral flange can inhibit dysphotopsia. By way of example, the peripheral flange can include at least one textured surface that is adapted to receive peripheral light rays entering the eye at large visual angles so as to cause their scattering in order to inhibit dysphotopsia, e.g., by preventing the formation of a secondary peripheral image or scattering some light to a shadow region between such a secondary image and an image formed by the IOL.

Abstract translation: 一方面，本发明提供了一种眼内透镜（IOL），其包括光学元件和围绕光学元件的外围光学法兰。 光学元件可以在IOL用户的视网膜上形成视场图像，并且外围法兰可以抑制异位斑。 作为示例，周边凸缘可以包括至少一个纹理表面，其适于以大的视角接收进入眼睛的周边光线，以便使其散射以便抑制异常斑，例如通过防止形成 二次周边图像或将一些光散射到这样的次级图像和由IOL形成的图像之间的阴影区域。

公开(公告)号：US20080269881A1

公开(公告)日：2008-10-30

申请号：US11741854

申请日：2007-04-30

Applicant: Michael J. Simpson ,  James M. Scott ,  Son Trung Tran

Inventor： Michael J. Simpson ,  James M. Scott ,  Son Trung Tran

IPC: A61F2/16

CPC classification number: A61F2/1613 ,  A61F2002/1683 ,  A61F2002/1696 ,  A61F2002/1699 ,  A61F2250/0014

Abstract: Asymmetric intraocular lenses (IOLs) are disclosed in which the centration of the optic and the pupil can be adjusted in order to reduce dsyphotopsia and/or the perception of dark shadows. For example, IOLs with uneven haptics are disclosed such that the center of the optic (i.e., the optical axis) is offset from a centerline of the overall device.

Abstract translation: 公开了不对称眼内透镜（IOL），其中可以调整光学元件和瞳孔的中心以便减少双重眼睛和/或暗影的感知。 例如，公开了具有不均匀触觉的IOL，使得光学器件的中心（即，光轴）偏离整个装置的中心线。

公开(公告)号：US08556421B2

公开(公告)日：2013-10-15

申请号：US13276965

申请日：2011-10-19

Applicant: Michael J. Simpson

Inventor： Michael J. Simpson

IPC: A61B3/10 ,  A61F2/16

CPC classification number: A61F2/16 ,  A61B3/0025

Abstract: In certain embodiments, calculating intraocular lens (IOL) power includes determining locations of parts of an eye along an axis of the eye. The locations include the location of a cornea, the anterior and posterior locations of a crystalline lens, and the location of a retina. An IOL location of an IOL is calculated according to the anterior and posterior locations of the crystalline lens. Corneal data is also determined. The IOL power is calculated using the corneal data, the IOL location, and the retinal location. In certain embodiments, refractive indices are determined for segments of the axis, and at least one location is adjusted according to the refractive indices.

公开(公告)号：US20130100408A1

公开(公告)日：2013-04-25

申请号：US13276965

申请日：2011-10-19

Applicant: Michael J. Simpson

Inventor： Michael J. Simpson

IPC: A61B3/10 ,  A61B3/00

CPC classification number: A61F2/16 ,  A61B3/0025

Abstract: In certain embodiments, calculating intraocular lens (IOL) power includes determining locations of parts of an eye along an axis of the eye. The locations include the location of a cornea, the anterior and posterior locations of a crystalline lens, and the location of a retina. An IOL location of an IOL is calculated according to the anterior and posterior locations of the crystalline lens. Corneal data is also determined. The IOL power is calculated using the corneal data, the IOL location, and the retinal location. In certain embodiments, refractive indices are determined for segments of the axis, and at least one location is adjusted according to the refractive indices.

Abstract translation: 在某些实施例中，计算人工晶状体（IOL）功率包括确定沿着眼睛的轴线的眼睛部分的位置。 位置包括角膜的位置，晶状体的前部和后部位置以及视网膜的位置。 根据晶状体的前部和后部位置计算IOL的IOL位置。 也确定角膜数据。 使用角膜数据，IOL位置和视网膜位置计算IOL功率。 在某些实施例中，针对轴的段确定折射率，并且根据折射率调整至少一个位置。

公开(公告)号：US20100131060A1

公开(公告)日：2010-05-27

申请号：US12621613

申请日：2009-11-19

Applicant: Michael J. Simpson ,  Krishnakumar Venkateswaran

Inventor： Michael J. Simpson ,  Krishnakumar Venkateswaran

IPC: A61F2/16

CPC classification number: A61F2/1618 ,  A61F2/1654 ,  G02C7/041 ,  G02C2202/20

Abstract: The present invention generally provides multifocal ophthalmic lenses, e.g., multifocal intraocular lenses, that employ a central refractive region for providing a refractive focusing power and a diffractive region for providing diffractive focusing powers. The refractive focusing power provided by the lens's central region corresponds to a far-focusing power that is substantially equal to one of the diffractive focusing powers while the other diffractive power corresponds to a near-focusing power. The far-focusing power can be enhanced by changes to the phase of the central refractive region and/or changes to the curvature of the central refractive region.

Abstract translation: 本发明通常提供多焦点眼科镜片，例如多焦点眼内透镜，其使用用于提供折射聚焦功能的中心折射区域和用于提供衍射聚焦光焦度的衍射区域。 由透镜的中心区域提供的折射聚焦功率对应于基本上等于衍射聚焦光焦度之一的远焦点光焦度，而另一衍射光焦度对应于近聚焦光焦度。 可以通过改变中心折射区域的相位和/或改变中心折射区域的曲率来增强远聚焦功率。

公开(公告)号：US20080269885A1

公开(公告)日：2008-10-30

申请号：US11741841

申请日：2007-04-30

Applicant: Michael J. Simpson ,  K. Scott Ellis

Inventor： Michael J. Simpson ,  K. Scott Ellis

IPC: A61F2/16

CPC classification number: A61F2/1613 ,  A61F2002/1699

Abstract: An IOL is disclosed that includes an anterior surface and a posterior surface disposed about an optical axis, where the posterior surface includes a central region extending to a peripheral region. Once the IOL is implanted in a patient's eye, the anterior surface and the central region of the posterior surface cooperatively form an image of a field of view on the retina and the peripheral region of the posterior surface directs at least some light rays incident thereon (e.g., via refraction by the anterior surface) to at least one retinal location offset from the image so as to inhibit dysphotopsia.

Abstract translation: 公开了一种IOL，其包括围绕光轴设置的前表面和后表面，其中后表面包括延伸到周边区域的中心区域。 一旦将IOL植入患者眼睛中，后表面的前表面和中心区域协同地形成视网膜上的视野图像，并且后表面的周边区域引导入射到其上的至少一些光线（ 例如通过前表面的折射）到偏离图像的至少一个视网膜位置，以便抑制失调。