公开(公告)号：US11628241B2

公开(公告)日：2023-04-18

申请号：US16624944

申请日：2018-06-22

Applicant: NIPRO CORPORATION

Inventor： Mitsutaka Ueda ,  Hidetoshi Saio

IPC: A61M1/16 ,  A61M1/30 ,  A61M1/34

Abstract: A blood purification apparatus that includes a blood purifier, a vascular access flow path, a cleaning solution flow path, and a drainage flow path. The blood purifier has an inner portion divided by a semi-permeable membrane into a first portion and a second portion. The vascular access flow path is connected to the blood purifier and is in communication with the first portion. The cleaning solution flow path is connected to the blood purifier and is in communication with the first portion. The drainage flow path is connected to the blood purifier and is in communication with the second portion. The cleaning solution flow path is provided with a blood pump capable of bidirectionally feeding a fluid. An open-close valve is provided in each of the vascular access flow path and the drainage flow path.

公开(公告)号：US11467170B2

公开(公告)日：2022-10-11

申请号：US16622373

申请日：2018-07-17

Applicant: NIPRO CORPORATION

Inventor： Toru Shinzato ,  Wataru Mizuno ,  Hidetoshi Saio

IPC: G01N33/72 ,  G01N33/48

Abstract: A dose determination program for an erythropoiesis-stimulating agent that is executable by a computer. The program causes the computer to perform: obtaining a predetermined target hemoglobin concentration; obtaining a first concentration and a first dose in a stable state in which a hemoglobin concentration is stable at the first concentration by repeatedly administering the first dose a plurality of times, and calculating a second dose of the erythropoiesis-stimulating agent based on the obtained target hemoglobin concentration, the obtained first concentration, and the obtained first dose, the second dose of the erythropoiesis-stimulating agent being to be administered by a fixed amount.