公开(公告)号：US20240416092A1

公开(公告)日：2024-12-19

申请号：US18821824

申请日：2024-08-30

Applicant: Nephronyx Ltd.

Inventor： Sagy KARAVANY ,  Eyal TEICHMAN

IPC: A61M27/00 ,  A61B18/00 ,  A61F2/06 ,  A61F2/82 ,  A61M25/00 ,  A61M60/122

Abstract: The devices and methods described herein include an implantable body lumen fluid flow modulator including an upstream flow accelerator separated by a gap from a downstream flow decelerator. The gap is a pathway to entrain additional fluid from a branch lumen(s) into the fluid stream flowing from the upstream flow accelerator to the downstream flow decelerator.

公开(公告)号：US20230190444A1

公开(公告)日：2023-06-22

申请号：US17999367

申请日：2021-05-26

Applicant: Nephronyx Ltd.

Inventor： Menashe YACOBY ,  Oren ROTMAN ,  Sagy KARAVANY ,  Tanhum FELD ,  Eyal TEICHMAN

IPC: A61F2/07 ,  A61F2/966 ,  A61F2/92

CPC classification number: A61F2/07 ,  A61F2/966 ,  A61F2/92 ,  A61F2002/068

Abstract: The acute and chronic devices and methods described herein include a body lumen fluid flow modulator including an upstream flow accelerator and a downstream flow decelerator. The fluid flow modulator preferably includes one or more openings that define a gap/entrainment region that provides a pathway through which additional fluid from a branch lumen(s) is entrained into the fluid stream flowing from the upstream flow accelerator to the downstream flow decelerator. Delivery devices including a sheath and inner assembly also are provided for delivering the flow modulator to the body lumen. The delivery device may maintain the flow modulator in its collapsed, delivery state upon retraction of the sheath for ease of readjustment within the body lumen prior to full deployment of the flow modulator within the body lumen.

公开(公告)号：US20250025284A1

公开(公告)日：2025-01-23

申请号：US18714554

申请日：2022-11-02

Applicant: Nephronyx Ltd.

Inventor： Sagy KARAVANY ,  Oren Moshe ROTMAN ,  Menashe YACOBY ,  Tanhum FELD

IPC: A61F2/07 ,  A61F2/06

Abstract: The acute and chronic devices and methods described herein include a body lumen fluid flow modulator including an upstream flow accelerator and a downstream flow decelerator. The fluid flow modulator preferably includes one or more openings that define a gap/entrainment region that provides a pathway through which additional fluid from a branch lumen(s) is entrained into the fluid stream flowing from the upstream flow accelerator to the downstream flow decelerator. The upstream flow accelerator may include a radially expandable portion that expands responsive to upstream pressures within the body lumen to accommodate a wider range of fluid flow rates. Additionally, the flow modulator may include a plurality of collapsible fixation elements for securing the flow modulator within the body lumen.

公开(公告)号：US20230218872A1

公开(公告)日：2023-07-13

申请号：US18180083

申请日：2023-03-07

Applicant: Nephronyx Ltd.

Inventor： Sagy KARAVANY ,  Eyal TEICHMAN

IPC: A61M27/00 ,  A61M25/00 ,  A61F2/82 ,  A61M60/122 ,  A61F2/06 ,  A61B18/00

CPC classification number: A61M27/002 ,  A61F2/06 ,  A61F2/82 ,  A61M25/0023 ,  A61M60/122 ,  A61B2018/00511 ,  A61B2018/00744 ,  A61F2002/065 ,  A61F2002/068 ,  A61F2230/001 ,  A61F2230/0067

Abstract: The devices and methods described herein include an implantable body lumen fluid flow modulator including an upstream flow accelerator separated by a gap from a downstream flow decelerator. The gap is a pathway to entrain additional fluid from a branch lumen(s) into the fluid stream flowing from the upstream flow accelerator to the downstream flow decelerator.

公开(公告)号：US20220117765A1

公开(公告)日：2022-04-21

申请号：US17646114

申请日：2021-12-27

Applicant: Nephronyx Ltd.

Inventor： Menashe YACOBY ,  Oren ROTMAN ,  Sagy KARAVANY ,  Tanhum FELD ,  Eyal TEICHMAN

IPC: A61F2/966 ,  A61F2/07

Abstract: The acute and chronic devices and methods described herein include a body lumen fluid flow modulator including an upstream flow accelerator and a downstream flow decelerator. The fluid flow modulator preferably includes one or more openings that define a gap/entrainment region that provides a pathway through which additional fluid from a branch lumen(s) is entrained into the fluid stream flowing from the upstream flow accelerator to the downstream flow decelerator. Delivery devices including a sheath and inner assembly also are provided for delivering the flow modulator to the body lumen. The delivery device may maintain the flow modulator in its collapsed, delivery state upon retraction of the sheath for ease of readjustment within the body lumen prior to full deployment of the flow modulator within the body lumen.