公开(公告)号：US20240189091A1

公开(公告)日：2024-06-13

申请号：US18505830

申请日：2023-11-09

Applicant: THRU-FLO ENDOVASCULAR, INC.

Inventor： George P. Teitelbaum

IPC: A61F2/06 ,  A61F2/82 ,  A61F2/90 ,  A61F2/95 ,  A61F2/954 ,  B29D23/00

CPC classification number: A61F2/06 ,  A61F2/90 ,  A61F2/954 ,  A61F2002/065 ,  A61F2002/068 ,  A61F2002/823 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2210/0014 ,  A61F2240/001 ,  B29D23/003

Abstract: A flow diversion device for treating branch point aneurysms that includes a wire stent frame comprising a plurality of wire elements, the wire stent comprising a proximal limb and two distal limbs, wherein the proximal limb and the two distal limbs converge at a crotch of the wire stent frame. The plurality of wire elements may be braided together. The flow diversion device may have a substantially Y-shape or T-shape. The flow diversion device may be manufactured by using two tubular flow diversion devices to make a Y-shaped flow diversion device.

公开(公告)号：US20240099882A1

公开(公告)日：2024-03-28

申请号：US18328074

申请日：2023-06-02

Applicant: J.D. Franco & Co., LLC

Inventor： Robert VIDLUND ,  Michael Calhoun ,  Jeff Franco

IPC: A61F9/007 ,  A61F2/06 ,  A61F2/856

CPC classification number: A61F9/007 ,  A61F2/06 ,  A61F2/856 ,  A61F2002/068 ,  A61F2/14 ,  A61F2210/0014 ,  A61F2230/0067

Abstract: A method of treating an eye of a patient may include positioning an expandable strut structure within at least one of an internal carotid artery, an ophthalmic artery, or an ostium at a junction between the internal carotid artery and the ophthalmic artery. Additionally, the method may include directing blood flow towards the ophthalmic artery via a diverter element associated with the expandable strut structure.

公开(公告)号：US11850142B2

公开(公告)日：2023-12-26

申请号：US17399946

申请日：2021-08-11

Applicant: THRU-FLO ENDOVASCULAR, INC.

Inventor： George P. Teitelbaum

IPC: A61F2/06 ,  A61F2/90 ,  A61F2/954 ,  A61F2/95 ,  B29D23/00 ,  A61F2/82

CPC classification number: A61F2/06 ,  A61F2/90 ,  A61F2/954 ,  A61F2002/065 ,  A61F2002/068 ,  A61F2002/823 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2210/0014 ,  A61F2240/001 ,  B29D23/003

Abstract: A flow diversion device for treating branch point aneurysms that includes a wire stent frame comprising a plurality of wire elements, the wire stent comprising a proximal limb and two distal limbs, wherein the proximal limb and the two distal limbs converge at a crotch of the wire stent frame. The plurality of wire elements may be braided together. The flow diversion device may have a substantially Y-shape or T-shape. The flow diversion device may be manufactured by using two tubular flow diversion devices to make a Y-shaped flow diversion device.

公开(公告)号：US20230293283A1

公开(公告)日：2023-09-21

申请号：US17584887

申请日：2022-01-26

Applicant: Sonorous, NV

Inventor： Randall Takahashi ,  Dawson Le ,  Dave Ferrera

IPC: A61F2/06

CPC classification number: A61F2/06 ,  A61F2002/0081 ,  A61F2002/068 ,  A61F2210/0076

Abstract: New devices use baffles and multiple diameters to treat and prevent ringing in the ears by altering pressure gradients in subject sinuses/vessels. Novel braided stents with variable radial force based upon wires added and woven allows 7-11 cm therapies, for example, to resolve pulsatile tinnitus in patients under conscious sedation.

公开(公告)号：US20230218872A1

公开(公告)日：2023-07-13

申请号：US18180083

申请日：2023-03-07

Applicant: Nephronyx Ltd.

Inventor： Sagy KARAVANY ,  Eyal TEICHMAN

IPC: A61M27/00 ,  A61M25/00 ,  A61F2/82 ,  A61M60/122 ,  A61F2/06 ,  A61B18/00

CPC classification number: A61M27/002 ,  A61F2/06 ,  A61F2/82 ,  A61M25/0023 ,  A61M60/122 ,  A61B2018/00511 ,  A61B2018/00744 ,  A61F2002/065 ,  A61F2002/068 ,  A61F2230/001 ,  A61F2230/0067

Abstract: The devices and methods described herein include an implantable body lumen fluid flow modulator including an upstream flow accelerator separated by a gap from a downstream flow decelerator. The gap is a pathway to entrain additional fluid from a branch lumen(s) into the fluid stream flowing from the upstream flow accelerator to the downstream flow decelerator.

公开(公告)号：US11672651B2

公开(公告)日：2023-06-13

申请号：US16784775

申请日：2020-02-07

Applicant: CARNEGIE MELLON UNIVERSITY ,  UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

Inventor： Masahiro Yoshida ,  C. Douglas Bernstein ,  Onur Dur ,  Kerem Pekkan

IPC: A61F2/24 ,  A61F2/06 ,  A61L27/16 ,  A61L33/00 ,  A61L27/24 ,  A61L27/36 ,  A61L27/58

CPC classification number: A61F2/2412 ,  A61F2/06 ,  A61F2/2403 ,  A61F2/2409 ,  A61F2/2415 ,  A61F2/2475 ,  A61L27/16 ,  A61L27/24 ,  A61L27/367 ,  A61L27/58 ,  A61L33/0011 ,  A61F2002/068 ,  A61F2250/0037 ,  A61F2250/0067 ,  A61F2250/0082 ,  A61L2430/20 ,  Y10T29/49412 ,  A61L27/16 ,  C08L27/18

Abstract: Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.

公开(公告)号：US11648103B2

公开(公告)日：2023-05-16

申请号：US16215690

申请日：2018-12-11

Applicant: UNIVERSITÄTSSPITAL BASEL

Inventor： Bernhard Winkler ,  Martin Grapow ,  Friedrich Eckstein ,  Aldo Ferrari ,  Dimos Poulikakos ,  Simone Bottan ,  Maximilian Fischer ,  Tobias Lendenmann

IPC: A61F2/07 ,  A61F2/06 ,  A61F2/90 ,  A61F2/00 ,  C12N1/20

CPC classification number: A61F2/07 ,  A61F2/06 ,  A61F2/062 ,  A61F2/90 ,  A61F2002/0086 ,  A61F2002/068 ,  A61F2002/072 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2250/003 ,  A61F2250/0026 ,  A61F2250/0051 ,  A61F2310/00011 ,  A61F2310/00982 ,  C12N1/20

Abstract: The invention relates to an artificial vascular graft comprising a primary scaffold structure encompassing an inner space of the artificial vascular graft, said primary scaffold structure having an inner surface facing towards said inner space and an outer surface facing away from said inner space, a coating on said inner surface, wherein a plurality of grooves is comprised in said coating of said inner surface. The primary scaffold structure comprises further a coating on said outer surface. The primary scaffold structure and the coating on said inner surface and on said outer surface are d designed in such a way that cells, in particular progenitor cells, can migrate from the periphery of said artificial vascular graft through said outer surface of said coating, said primary scaffold structure and said inner surface to said inner space, if the artificial vascular graft is used as intended. The invention relates further to a method for providing said graft.

公开(公告)号：US20190209351A1

公开(公告)日：2019-07-11

申请号：US16357812

申请日：2019-03-19

Applicant: Q3 MEDICAL DEVICES LIMITED

Inventor： Eric K. MANGIARDI

IPC: A61F2/844 ,  A61B17/72 ,  A61F2/82

CPC classification number: A61F2/844 ,  A61B17/7233 ,  A61B17/7258 ,  A61B17/7266 ,  A61B17/7283 ,  A61B17/7291 ,  A61F2/06 ,  A61F2/82 ,  A61F2002/041 ,  A61F2002/048 ,  A61F2002/068 ,  A61F2002/30289 ,  A61F2230/0091

Abstract: A stent is disclosed that has an elongated body composed of a bioabsorbable polymer having a proximal end, a distal end, two open spiral channels formed on the exterior surface of the body to provide fluid communication between the proximal end and the distal end. The stent has a central lumen open at the proximal and distal ends of the stent for the passage of a guide wire. The stent also has an anti-migration device used for immobilization of the stent at the target site.

公开(公告)号：US20180325708A1

公开(公告)日：2018-11-15

申请号：US15775332

申请日：2016-11-10

Applicant: Noureddine FRID ,  Cardiatis S.A.

Inventor： Noureddine Frid

IPC: A61F2/90

CPC classification number: A61F2/90 ,  A61F2002/068 ,  A61F2002/823 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2230/0069

Abstract: The present invention refers to an implantable endoluminal prosthesis for use in the treatment of aneurysm involving branches having a multilayer configuration, comprising at least one self-expandable braided framework extending along an axis able to expand from a radially compressed state in a delivery configuration to a radially expanded state; the self-expandable braided framework being formed with at most 196 wires having a given wire diameter (Ø21); this self-expandable braided framework devoid of any impermeable cover layer, comprising a plurality of layers of wires made of biocompatible material; and forming a wall of the endoluminal prosthesis; each layer forming a mesh; the meshes forming a lattice with a plurality of wires of said layers; the meshes being interlocked, the wires being integrated in the mesh of at least one of the adjacent layers; the self-expandable braided framework comprising a lumen in a cylindrical form with a circular cross-section and a constant diameter; characterized in that, in radially expanded state, a ratio (T1/Ø21) of thickness (T1) of a wall of the implantable endoluminal prosthesis in radially expanded state to the diameter (Ø21) of wire (21) being greater than 3.0; and the surface coverage ratio (SCR) of said braided framework is at least 30% and at most 50%.

公开(公告)号：US20180256312A1

公开(公告)日：2018-09-13

申请号：US15800687

申请日：2017-11-01

Applicant: The General Hospital Corporation ,  The Charles Stark Draper Laboratory

Inventor： David M. Hoganson ,  Howard I. Pryor ,  Ira Spool ,  Joseph P. Vacanti ,  Jeffrey T. Borenstein

IPC: A61F2/06 ,  A61F2/04 ,  A61F2/02 ,  G01N33/50

CPC classification number: A61F2/062 ,  A61F2/022 ,  A61F2/04 ,  A61F2/06 ,  A61F2002/068 ,  G01N33/5008

Abstract: The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e). The invention also provides compositions comprising a vascular layer for use in tissue lamina as well as a medical devices having a vascular layer and kits.