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公开(公告)号：US20180273984A1
公开(公告)日：2018-09-27
申请号：US16006521
申请日：2018-06-12
IPC分类号： C12P7/10
摘要： The invention relates to a process of detoxifying pre-treated lignocellulose-containing material comprising subjecting the pre-treated lignocellulose-containing material to one or more phenolic compound oxidizing enzymes.
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公开(公告)号：US11840696B2
公开(公告)日：2023-12-12
申请号：US16506201
申请日：2019-07-09
申请人： Novozymes A/S
发明人： Qiming Jin , Jeffrey Shasky , Donna Moyer , Abigail Jang , Gloria Muzzi-Erichsen , Cara Kleindienst
CPC分类号： C12N15/79 , C12N15/902 , C12N2800/30
摘要： The present invention relates to methods of introducing multiple expression constructs into a eukaryotic cell, methods of constructing a eukaryotic cell having multiple target loci for expressing multiple heterologous proteins of interest, eukaryotic cells for expressing multiple heterologous proteins of interest, and methods of production of multiple heterologous proteins of interest.
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公开(公告)号：US10385352B2
公开(公告)日：2019-08-20
申请号：US15556439
申请日：2016-03-09
申请人： Novozymes A/S
发明人： Qiming Jin , Jeffrey Shasky , Donna Moyer , Abigail Jang , Gloria Muzzi-Erichsen , Cara Kleindienst
摘要： The present invention relates to methods of introducing multiple expression constructs into a eukaryotic cell, methods of constructing a eukaryotic cell having multiple target loci for expressing multiple heterologous proteins of interest, eukaryotic cells for expressing multiple heterologous proteins of interest, and methods of production of multiple heterologous proteins of interest.
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公开(公告)号：US20180037897A1
公开(公告)日：2018-02-08
申请号：US15556439
申请日：2016-03-09
申请人： Novozymes A/S
发明人： Qiming Jin , Jeffrey Shasky , Donna Moyer , Abigail Jang , Gloria Muzzi-Erichsen , Cara Kleindienst
CPC分类号： C12N15/79 , C12N15/902 , C12N2800/30
摘要： The present invention relates to methods of introducing multiple expression constructs into a eukaryotic cell, methods of constructing a eukaryotic cell having multiple target loci for expressing multiple heterologous proteins of interest, eukaryotic cells for expressing multiple heterologous proteins of interest, and methods of production of multiple heterologous proteins of interest.
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公开(公告)号：US20190330644A1
公开(公告)日：2019-10-31
申请号：US16506201
申请日：2019-07-09
申请人： Novozymes A/S
发明人： Qiming Jin , Jeffrey Shasky , Donna Moyer , Abigail Jang , Gloria Muzzi-Erichsen , Cara Kleindienst
摘要： The present invention relates to methods of introducing multiple expression constructs into a eukaryotic cell, methods of constructing a eukaryotic cell having multiple target loci for expressing multiple heterologous proteins of interest, eukaryotic cells for expressing multiple heterologous proteins of interest, and methods of production of multiple heterologous proteins of interest.
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公开(公告)号：US20170260520A1
公开(公告)日：2017-09-14
申请号：US15505196
申请日：2015-08-20
申请人： Novozymes A/S
CPC分类号： C12N15/1082 , C12N15/63 , C12P21/00
摘要： The present invention provides methods for integrating a polynucleotide library of interest in the chromosome of a filamentous fungal host cell using a site-specific recombinase, polynucleotide library expression systems comprising a host cell and a polynucleotide construct, as well as the resulting filamentous fungal host cells comprising a polynucleotide library and their cultivation to produce a polypeptide.
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7.发明申请公开(公告)号：US20190249161A1
公开(公告)日：2019-08-15
申请号：US16394951
申请日：2019-04-25
申请人： Novozymes, Inc.
发明人： Debbie Yaver , Qiming Jin
CPC分类号： C12N9/2437 , C12N9/2402 , C12N15/80 , C12N15/87 , C12Y302/01091 , C12Y302/0115
摘要： The present invention relates to methods for constructing a filamentous fungal strain for production of multiple recombinant polypeptides having biological activity. The present invention also relates to methods for producing multiple recombinant polypeptides having biological activity in a filamentous fungal strain. The present invention also relates to filamentous fungal strains expressing multiple recombinant polypeptides having biological activity.
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公开(公告)号：US10301610B2
公开(公告)日：2019-05-28
申请号：US15280706
申请日：2016-09-29
申请人： Novozymes, Inc.
发明人： Debbie Yaver , Qiming Jin
摘要： The present invention relates to methods for constructing a filamentous fungal strain for production of multiple recombinant polypeptides having biological activity. The present invention also relates to methods for producing multiple recombinant polypeptides having biological activity in a filamentous fungal strain. The present invention also relates to filamentous fungal strains expressing multiple recombinant polypeptides having biological activity.
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9.发明授权公开(公告)号：US10822601B2
公开(公告)日：2020-11-03
申请号：US16394951
申请日：2019-04-25
申请人： Novozymes, Inc.
发明人： Debbie Yaver , Qiming Jin
摘要： The present invention relates to methods for constructing a filamentous fungal strain for production of multiple recombinant polypeptides having biological activity. The present invention also relates to methods for producing multiple recombinant polypeptides having biological activity in a filamentous fungal strain. The present invention also relates to filamentous fungal strains expressing multiple recombinant polypeptides having biological activity.
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10.发明申请Methods For Producing Multiple Recombinant Polypeptides In A Filamentous Fungal Host Cell 审中-公开在丝状真菌宿主细胞中产生多种重组多肽的方法公开(公告)号：US20170015986A1
公开(公告)日：2017-01-19
申请号：US15280706
申请日：2016-09-29
申请人： Novozymes, Inc.
发明人： Debbie Yaver , Qiming Jin
CPC分类号： C12N9/2437 , C12N9/2402 , C12N15/80 , C12N15/87 , C12Y302/01091 , C12Y302/0115
摘要： The present invention relates to methods for constructing a filamentous fungal strain for production of multiple recombinant polypeptides having biological activity. The present invention also relates to methods for producing multiple recombinant polypeptides having biological activity in a filamentous fungal strain. The present invention also relates to filamentous fungal strains expressing multiple recombinant polypeptides having biological activity.
摘要翻译： 本发明涉及构建用于生产具有生物活性的多重重组多肽的丝状真菌菌株的方法。 本发明还涉及在丝状真菌菌株中生产具有生物活性的多重重组多肽的方法。 本发明还涉及表达具有生物活性的多种重组多肽的丝状真菌菌株。
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