公开(公告)号：US11848183B2

公开(公告)日：2023-12-19

申请号：US16727454

申请日：2019-12-26

Applicant: Ohio State Innovation Foundation

Inventor： Vicki Wysocki ,  Joshua Gilbert ,  Alyssa Stiving

IPC: H01J49/00 ,  H01J49/06

CPC classification number: H01J49/0068 ,  H01J49/062

Abstract: Devices and methods for surface-induced dissociation (SID) are disclosed. In one aspect, a device for SID is disclosed which, in one embodiment includes a collision surface, a deflector configured to guide precursor ions from a pre-SID region to the collision surface to cause SID, and an ion carpet having applied electrical properties configured to guide product ions resulting from collision with the collision surface to a post-SID region. In another aspect, a method for SID is disclosed which, in one embodiment includes guiding, by a deflector, precursor ions from a pre-SID region to a collision surface to cause SID, and guiding, by an ion carpet having selected applied electrical properties, product ions resulting from collision with the collision surface to a post-SID region.

公开(公告)号：US20200273687A1

公开(公告)日：2020-08-27

申请号：US16727454

申请日：2019-12-26

Applicant: Ohio State Innovation Foundation

Inventor： Vicki Wysocki ,  Joshua Gilbert ,  Alyssa Stiving

IPC: H01J49/00 ,  H01J49/06

Abstract: Devices and methods for surface-induced dissociation (SID) are disclosed. In one aspect, a device for SID is disclosed which, in one embodiment includes a collision surface, a deflector configured to guide precursor ions from a pre-SID region to the collision surface to cause SID, and an ion carpet having applied electrical properties configured to guide product ions resulting from collision with the collision surface to a post-SID region. In another aspect, a method for SID is disclosed which, in one embodiment includes guiding, by a deflector, precursor ions from a pre-SID region to a collision surface to cause SID, and guiding, by an ion carpet having selected applied electrical properties, product ions resulting from collision with the collision surface to a post-SID region.

公开(公告)号：US12176196B2

公开(公告)日：2024-12-24

申请号：US17431299

申请日：2019-12-15

Applicant: Ohio State Innovation Foundation

Inventor： Vicki Wysocki ,  Dalton Snyder ,  Benjamin Jones ,  Alyssa Stiving ,  Joshua Gilbert ,  Zachary Vanaernum ,  Sophie Harvey-Bernier

IPC: H01J49/00 ,  H01J49/06 ,  H01J49/38 ,  H01J49/42

Abstract: Devices and methods for surface-induced association are disclosed herein. According to one embodiment, a device for surface-induced dissociation (SID) includes a collision surface and a deflector configured to guide precursor ions from a pre-SID region to the collision surface. In some embodiments, an extractor extracts ions off the collision surface after collision with the collision surface. In some embodiments, an RF device can collect and/or transmit the extracted ions. In some embodiments, an ion funnel guides product ions resulting from collision with the collision surface to a post-SID region. Some aspects of the disclosure are directed to methods for surface-induced dissociation, which may in some embodiments include using of a split lens or an ion funnel.