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公开(公告)号:US20210205473A1
公开(公告)日:2021-07-08
申请号:US17057415
申请日:2019-05-23
发明人: K. Craig Kent , Shaoqin Gong , Lianwang Guo , Bowen Wang , Guojun Chen , Go Urabe
摘要: The present disclosure relates to unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. The disclosed compositions are useful for treating a subject with a disease or condition, such as a cardiovascular disease. In a further aspect, the cardiovascular disease can be a vascular stenosis or restenosis. Also described herein are methods of making and using the unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
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公开(公告)号:US11446392B2
公开(公告)日:2022-09-20
申请号:US17057415
申请日:2019-05-23
发明人: K. Craig Kent , Shaoqin Gong , Lianwang Guo , Bowen Wang , Guojun Chen , Go Urabe
摘要: The present disclosure relates to unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. The disclosed compositions are useful for treating a subject with a disease or condition, such as a cardiovascular disease. In a further aspect, the cardiovascular disease can be a vascular stenosis or restenosis. Also described herein are methods of making and using the unimolecular core-shell nanoparticle, nanoclusters thereof, and platelet biomimetic nanoclusters thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
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