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公开(公告)号：US20240181071A1
公开(公告)日：2024-06-06
申请号：US18492055
申请日：2023-10-23
Applicant: Pfizer Inc.
Inventor： Andrea Therese HOOPER , Kimberly Ann MARQUETTE , Chakrapani SUBRAMANYAM , Hans-Peter GERBER , Chad Michael MAY
CPC classification number: A61K47/6803 , A61K47/6843 , A61P35/00 , C07K16/18 , A61K38/08 , A61K47/6811
Abstract: The present invention provides antibodies and antibody-drug conjugates that bind to the extra domain B splice variant of fibronectin 1 and methods for preparing and using the same.
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Patent Agency Ranking
公开(公告)号：US20240261423A1
公开(公告)日：2024-08-08
申请号：US18528539
申请日：2023-12-04
Applicant: Pfizer Inc.
Inventor： Andrea Therese HOOPER , Kimberly Ann MARQUETTE , Chakrapani SUBRAMANYAM , Hans-Peter GERBER , Chad Michael MAY
CPC classification number: A61K47/6803 , A61K47/6843 , A61P35/00 , C07K16/18 , A61K38/08 , A61K47/6811 , C07K2317/21 , C07K2317/33 , C07K2317/52 , C07K2317/565 , C07K2317/92
Abstract: The present invention provides antibodies and antibody-drug conjugates that bind to the extra domain B splice variant of fibronectin 1 and methods for preparing and using the same.
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公开(公告)号：US20230241235A1
公开(公告)日：2023-08-03
申请号：US18166774
申请日：2023-02-09
Applicant: Pfizer Inc.
Inventor： Andrea Therese HOOPER , Kimberly Ann MARQUETTE , Chakrapani SUBRAMANYAM , Hans-Peter GERBER , Chad Michael MAY
CPC classification number: A61K47/6811 , A61K47/6843 , A61P35/00 , A61K38/08 , C07K16/18 , A61K47/6803 , C07K2317/21 , C07K2317/52 , C07K2317/565 , C07K2317/33 , C07K2317/92
Abstract: The present invention provides antibodies and antibody-drug conjugates that bind to the extra domain B splice variant of fibronectin 1 and methods for preparing and using the same.
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公开(公告)号：US20190269791A1
公开(公告)日：2019-09-05
申请号：US16342275
申请日：2017-10-03
Applicant: Pfizer Inc.
Inventor： Andrea Therese HOOPER , Kimberly Ann MARQUETTE , Chakrapani SUBRAMANYAM , Hans-Peter GERBER , Chad Michael MAY
Abstract: The present invention provides antibodies and antibody-drug conjugates that bind to the extra domain B splice variant of fibronectin 1 and methods for preparing and using the same.
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公开(公告)号：US20240156977A1
公开(公告)日：2024-05-16
申请号：US18492348
申请日：2023-10-23
Applicant: Pfizer Inc.
Inventor： Andrea Therese HOOPER , Kimberly Ann MARQUETTE , Chakrapani SUBRAMANYAM , Hans-Peter GERBER , Chad Michael MAY
CPC classification number: A61K47/6803 , A61K47/6843 , A61P35/00 , C07K16/18 , A61K38/08 , A61K47/6811
Abstract: The present invention provides antibodies and antibody-drug conjugates that bind to the extra domain B splice variant of fibronectin 1 and methods for preparing and using the same.
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公开(公告)号：US20160002357A1
公开(公告)日：2016-01-07
申请号：US14751704
申请日：2015-06-26
Applicant: Pfizer Inc.
Inventor： Chad Michael MAY , Adam Reid ROOT , William A. BRADY , Lioudmila Gennadievna TCHISTIAKOVA , Lidia MOSYAK , Laird BLOOM , Paul A. MOORE , Leslie S. JOHNSON
CPC classification number: C07K16/468 , C07K16/18 , C07K16/28 , C07K16/2809 , C07K2317/31 , C07K2317/524 , C07K2317/526 , C07K2317/56 , C07K2317/565 , C07K2317/626 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/94
Abstract: Bispecific heterodimeric diabody molecules and uses thereof in the treatment of cancer. The bispecific heterodimeric diabody molecules comprise two polypeptide chains that associate to form two epitope binding sites recognizing the P-cadherin tumor cell associated antigen and the CD3 T cell antigen.
Abstract translation: 双特异性二聚体双抗体分子及其在治疗癌症中的用途。 双特异性异二聚体双抗体分子包含两个多肽链，其连接形成识别P-钙粘蛋白肿瘤细胞相关抗原和CD3T细胞抗原的两个表位结合位点。
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