公开(公告)号：US11525010B2

公开(公告)日：2022-12-13

申请号：US16417863

申请日：2019-05-21

Applicant: Pfizer Inc.

Inventor： Chew Shun Chang ,  Gurkan Guntas ,  Madan Katragadda ,  Divya Mathur ,  Adam Reid Root ,  Lidia Mosyak ,  Edward Roland LaVallie

IPC: C07K16/40 ,  A61P35/00 ,  A61K45/06

Abstract: The present invention provides novel antibodies that specifically bind to GUCY2c and uses thereof in the treatment of cancer. The present invention further provides novel bispecific antibodies comprising such antibodies and uses thereof in the treatment of cancer.

公开(公告)号：US20200010566A1

公开(公告)日：2020-01-09

申请号：US16417863

申请日：2019-05-21

Applicant: Pfizer Inc.

Inventor： Chew Shun Chang ,  Gurkan Guntas ,  Madan Katragadda ,  Divya Mathur ,  Adam Reid Root ,  Lidia Mosyak ,  Edward Roland LaVallie

IPC: C07K16/40 ,  A61P35/00

Abstract: The present invention provides novel antibodies that specifically bind to GUCY2c and uses thereof in the treatment of cancer. The present invention further provides novel bispecific antibodies comprising such antibodies and uses thereof in the treatment of cancer.