公开(公告)号：US10544212B2

公开(公告)日：2020-01-28

申请号：US15495172

申请日：2017-04-24

Applicant: Pfizer Inc.

Inventor： Laird Bloom ,  Karl Henry Nocka ,  James Reasoner Apgar ,  Matthew Allister Lambert ,  Mark A. Farmer

IPC: C07K16/24 ,  A61K39/395 ,  A61K39/00

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to IL-33, as well as uses, and associated methods thereof.

公开(公告)号：US20200055930A1

公开(公告)日：2020-02-20

申请号：US16541817

申请日：2019-08-15

Applicant: Pfizer Inc.

Inventor： Kevin Charles Beaumont ,  Danna M. Breen ,  Matthew Allister Lambert ,  Jeffrey Raymond Chabot ,  Tao He ,  Ksenya Shchors ,  James R. Apgar

IPC: C07K16/22 ,  A61P35/00

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to GDF15, as well as methods and uses for the antibodies.

公开(公告)号：US11566066B2

公开(公告)日：2023-01-31

申请号：US16541817

申请日：2019-08-15

Applicant: Pfizer Inc.

Inventor： Kevin Charles Beaumont ,  Danna M. Breen ,  Matthew Allister Lambert ,  Jeffrey Raymond Chabot ,  Tao He ,  Ksenya Shchors ,  James R. Apgar

IPC: C07K16/22 ,  C12N5/10 ,  C12N15/63 ,  A61P35/00 ,  C07K16/28 ,  C07K16/24

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to GDF15, as well as methods and uses for the antibodies.

公开(公告)号：US12227564B2

公开(公告)日：2025-02-18

申请号：US17816484

申请日：2022-08-01

Applicant: Pfizer Inc.

Inventor： Kevin Charles Beaumont ,  Danna M. Breen ,  Matthew Allister Lambert ,  Jeffrey Raymond Chabot ,  Tao He ,  Ksenya Shchors ,  James R. Apgar

IPC: A61K39/395 ,  A61P35/00 ,  C07K16/22 ,  C07K16/24 ,  C07K16/28 ,  C12N5/10 ,  C12N15/63

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to GDF15, as well as methods and uses for the antibodies.

公开(公告)号：US20220380448A1

公开(公告)日：2022-12-01

申请号：US17816484

申请日：2022-08-01

Applicant: Pfizer Inc.

Inventor： Kevin Charles Beaumont ,  Danna M. Breen ,  Matthew Allister Lambert ,  Jeffrey Raymond Chabot ,  Tao He ,  Ksenya Shchors ,  James R. Apgar

IPC: C07K16/22 ,  A61P35/00

Abstract: The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to GDF15, as well as methods and uses for the antibodies.