公开(公告)号：US20230365539A1

公开(公告)日：2023-11-16

申请号：US18226638

申请日：2023-07-26

Applicant: QATAR UNIVERSITY

Inventor： Ashraf KHALIL ,  Ala-Eddin AL MOUSTAFA ,  Dana H. ELKHALIFA ,  Feras ALALI

IPC: C07D405/10 ,  A61P35/00 ,  C07D295/033 ,  C07C225/22 ,  C07C317/30 ,  C07D413/10

CPC classification number: C07D405/10 ,  A61P35/00 ,  C07D295/033 ,  C07C225/22 ,  C07C317/30 ,  C07D413/10 ,  A61K45/06

Abstract: Provided herein are compounds, compositions, and methods useful for the treatment of breast cancer, particularly triple negative breast cancers. In certain aspects, provided herein are compounds of formula (I):




or a pharmaceutically acceptable salt or solvate thereof. In certain aspects, provided herein are compositions comprising any of the compounds provided herein. In certain aspects, provided herein are methods for the treatment of cancer in a subject in need thereof comprising administering to the subject an effective amount of any of the compounds or compositions provided herein.