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公开(公告)号：US20200155612A1
公开(公告)日：2020-05-21
申请号：US16630954
申请日：2018-07-16
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
Inventor： Sandu PITARU
Abstract: The present invention provides secretome derived from human oral mucosa stem cells (hOMSC), and cell-free compositions comprising hOMSC-derived secretome. Methods for obtaining, manipulating and using hOMSC-derived secretome in therapy, cosmetics and tissue regeneration are also provided.
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公开(公告)号：US20230416745A1
公开(公告)日：2023-12-28
申请号：US18366403
申请日：2023-08-07
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
Inventor： Sandu PITARU
IPC: C12N15/113 , A61P17/02
CPC classification number: C12N15/113 , A61P17/02 , C12Y115/01001 , A61K31/713
Abstract: The present invention provides secretome derived from human oral mucosa stem cells (hOMSC), and cell-free compositions comprising hOMSC-derived secretome. Methods for obtaining, manipulating and using hOMSC-derived secretome in therapy, cosmetics and tissue regeneration are also provided.
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公开(公告)号：US20180008648A1
公开(公告)日：2018-01-11
申请号：US15548120
申请日：2016-01-31
Inventor： Shulamit LEVENBERG , Sandu PITARU , Daniel OFFEN , Javier Ganz , Sivan Ida COHEN-MATSLIAH , Erez SHOR
CPC classification number: A61K35/38 , A61K9/0085 , A61L27/26 , A61L27/3604 , A61L27/3675 , A61L27/3834 , A61L27/3878 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/412 , A61L2300/414 , A61L2300/64 , A61L2430/32 , A61L2430/38 , C12N5/0632 , C12N2533/40 , C12N2533/56
Abstract: A method of treating a spinal cord injury in a subject in need thereof is disclosed. The method comprises implanting a scaffold into the spinal cord of a subject, wherein the scaffold is seeded with oral mucosa stem cells (OMSC) and/or cells that have been ex vivo differentiated from said OMSCs, thereby treating the spinal cord injury.
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