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1.发明申请公开(公告)号：US20210009660A1
公开(公告)日：2021-01-14
申请号：US15934055
申请日：2018-03-23
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Alfred Engel , Pavel Kubalec , Alfons Nichtl , Tobias Oelschlaegel , Rainer Schlecht
IPC: C07K16/00
Abstract: The disclosure describes a recombinant immunoglobulin heavy chain comprising a sortase conjugation loop, methods for conjugating and/or labeling such recombinant immunoglobulin heavy chains by use of the enzyme sortase and to the conjugates/labeled products obtained via the method.
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2.发明授权公开(公告)号：US11136376B2
公开(公告)日：2021-10-05
申请号：US15934055
申请日：2018-03-23
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Alfred Engel , Pavel Kubalec , Alfons Nichtl , Tobias Oelschlaegel , Rainer Schlecht
IPC: C07K16/00
Abstract: The disclosure describes a recombinant immunoglobulin heavy chain comprising a sortase conjugation loop, methods for conjugating and/or labeling such recombinant immunoglobulin heavy chains by use of the enzyme sortase and to the conjugates/labeled products obtained via the method.
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