-
1.发明授权Compounds for stabilizing ryanodine receptors from aberrant levels of calcium release 有权化合物用于稳定来自异常水平的钙释放的兰诺定受体公开(公告)号：US09102645B2
公开(公告)日：2015-08-11
申请号：US14213614
申请日：2014-03-14
Inventor： Grace E. Stutzmann , Russell Dahl , Christopher H. Kaiho
IPC: A61K31/4427 , A61K31/341 , A61K31/4166 , C07D307/52 , C07D405/12 , C07D307/54 , C07D407/12
CPC classification number: C07D307/52 , A61K31/341 , A61K31/4166 , A61K31/4427 , C07D307/54 , C07D405/12 , C07D407/12
Abstract: Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.
Abstract translation: 本文公开了包含能够使神经元钙发育不稳定性归一化的化合物的方法和组合物。 还公开了包括这些化合物用于治疗神经元或神经障碍的方法，包括阿尔茨海默病，帕金森病，亨廷顿舞蹈病，颞叶性痴呆，皮克病，慢性创伤性脑病，创伤性脑损伤，中风，小脑共济失调，多发性硬化症，唐氏综合征 ，和老化相关的中枢神经系统疾病。
-
Patent Agency Ranking
公开(公告)号：US10011578B2
公开(公告)日：2018-07-03
申请号：US15671833
申请日：2017-08-08
Inventor： Grace E. Stutzmann , Russell Dahl , Christopher H. Kaiho
IPC: C07D307/52 , C07D307/54 , C07D405/12 , C07D407/12
CPC classification number: C07D307/54 , C07D307/52 , C07D405/12 , C07D407/12
Abstract: Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.
-
公开(公告)号：US09725429B2
公开(公告)日：2017-08-08
申请号：US14716138
申请日：2015-05-19
Inventor： Grace E. Stutzmann , Russell Dahl , Christopher H. Kaiho
IPC: C07D307/54 , C07D405/12 , C07D307/52 , C07D407/12
CPC classification number: C07D307/54 , C07D307/52 , C07D405/12 , C07D407/12
Abstract: Disclosed herein are methods and compositions comprising compounds of formula (I) capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.
-
4.发明申请Compounds For Stabilizing Ryanodine Receptors From Aberrant Levels Of Calcium Release 有权用于稳定来自不稳定水平的钙释放的兰诺定受体的化合物公开(公告)号：US20160024038A1
公开(公告)日：2016-01-28
申请号：US14716138
申请日：2015-05-19
Inventor： Grace E. Stutzmann , Russell Dahl , Christopher H. Kaiho
IPC: C07D307/54 , C07D307/52 , C07D405/12
CPC classification number: C07D307/54 , C07D307/52 , C07D405/12 , C07D407/12
Abstract: Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.
Abstract translation: 本文公开了包含能够使神经元钙发育不稳定性归一化的化合物的方法和组合物。 还公开了包括这些化合物用于治疗神经元或神经障碍的方法，包括阿尔茨海默病，帕金森病，亨廷顿舞蹈病，颞叶性痴呆，皮克病，慢性创伤性脑病，创伤性脑损伤，中风，小脑共济失调，多发性硬化症，唐氏综合征 ，和老化相关的中枢神经系统疾病。
-
5.发明申请Compounds For Stabilizing Ryanodine Receptors From Aberrant Levels Of Calcium Release 有权用于稳定来自不稳定水平的钙释放的兰诺定受体的化合物公开(公告)号：US20140275112A1
公开(公告)日：2014-09-18
申请号：US14213614
申请日：2014-03-14
Inventor： Grace E. Stutzmann , Russell Dahl
IPC: C07D307/52 , C07D307/54 , C07D407/12 , C07D405/12
CPC classification number: C07D307/52 , A61K31/341 , A61K31/4166 , A61K31/4427 , C07D307/54 , C07D405/12 , C07D407/12
Abstract: Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.
Abstract translation: 本文公开了包含能够使神经元钙发育不稳定性归一化的化合物的方法和组合物。 还公开了包括这些化合物用于治疗神经元或神经障碍的方法，包括阿尔茨海默病，帕金森病，亨廷顿舞蹈病，颞叶性痴呆，皮克病，慢性创伤性脑病，创伤性脑损伤，中风，小脑共济失调，多发性硬化症，唐氏综合征 ，和老化相关的中枢神经系统疾病。
-
公开(公告)号：US20180022722A1
公开(公告)日：2018-01-25
申请号：US15671833
申请日：2017-08-08
Inventor： Grace E. Stutzmann , Russell Dahl , Christopher H. Kaiho
IPC: C07D307/54 , C07D307/52 , C07D407/12 , C07D405/12
CPC classification number: C07D307/54 , C07D307/52 , C07D405/12 , C07D407/12
Abstract: Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.
-
-
-
-
-
Search Results
6
records
(took 0.017 seconds)
