公开(公告)号：US09539553B2

公开(公告)日：2017-01-10

申请号：US14359635

申请日：2012-10-17

Applicant: Shiseido Company, Ltd.

Inventor： Yuki Sugiyama ,  Tomoko Sato ,  Ken Shoji

IPC: A61K8/06 ,  A61K8/81 ,  A61Q13/00 ,  B01F17/00 ,  A61Q19/00 ,  C08F290/06 ,  C08F220/18 ,  C11B9/00 ,  A61K8/91 ,  C08F220/14 ,  C08F220/28 ,  C08L33/10 ,  C08L33/12 ,  A61Q17/04

CPC classification number: B01F17/0028 ,  A61K8/062 ,  A61K8/8152 ,  A61K8/91 ,  A61K2800/10 ,  A61K2800/54 ,  A61K2800/95 ,  A61Q13/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/005 ,  B01F17/0021 ,  C08F220/14 ,  C08F220/18 ,  C08F220/28 ,  C08F290/062 ,  C08L33/10 ,  C08L33/12 ,  C11B9/00 ,  C08F2220/1825 ,  C08F2220/286 ,  C08F2222/1013

Abstract: The present invention provides a corona-core microgel emulsifying agent composed of a copolymer obtained by polymerizing polyethylene oxide macromonomers, hydrophobic monomers, and cross-linking monomers under specific conditions as well as an oil-in-water emulsified composition characteristically using said emulsifying agent for emulsification.The object of the present invention is to provide a new corona-core microgel emulsifying agent to be used to prepare an oil-in-water emulsified composition that manifests superior emulsification stability, stability over time, and low skin irritation, and is free of stickiness at the time of application, manifests dewy freshness, is free of powdery sensation and/or squeakiness, and is superior in durability of fragrance, as well as an oil-in-water emulsified composition emulsified with said emulsifying agent.

Abstract translation: 本发明的目的是提供一种新的电晕核微凝胶乳化剂，其用于制备水乳化组合物，其表现出优异的乳化稳定性，随时间的稳定性和低皮肤刺激性，并且不含粘性 在使用时，呈现露洁的新鲜感，无粉感和/或吱吱声，并且具有优异的香料耐久性，以及用所述乳化剂乳化的水包油型乳化组合物。

公开(公告)号：US20140343170A1

公开(公告)日：2014-11-20

申请号：US14359635

申请日：2012-10-17

Applicant: Shiseido Company, Ltd.

Inventor： Yuki Sugiyama ,  Tomoko Sato ,  Ken Shoji

IPC: A61K8/81 ,  C11B9/00 ,  A61Q19/00 ,  C08F220/18 ,  A61K8/06

CPC classification number: B01F17/0028 ,  A61K8/062 ,  A61K8/8152 ,  A61K8/91 ,  A61K2800/10 ,  A61K2800/54 ,  A61K2800/95 ,  A61Q13/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/005 ,  B01F17/0021 ,  C08F220/14 ,  C08F220/18 ,  C08F220/28 ,  C08F290/062 ,  C08L33/10 ,  C08L33/12 ,  C11B9/00 ,  C08F2220/1825 ,  C08F2220/286 ,  C08F2222/1013

Abstract: The present invention provides a corona-core microgel emulsifying agent composed of a copolymer obtained by polymerizing polyethylene oxide macromonomers, hydrophobic monomers, and cross-linking monomers under specific conditions as well as an oil-in-water emulsified composition characteristically using said emulsifying agent for emulsification.The object of the present invention is to provide a new corona-core microgel emulsifying agent to be used to prepare an oil-in-water emulsified composition that manifests superior emulsification stability, stability over time, and low skin irritation, and is free of stickiness at the time of application, manifests dewy freshness, is free of powdery sensation and/or squeakiness, and is superior in durability of fragrance, as well as an oil-in-water emulsified composition emulsified with said emulsifying agent.

Abstract translation: 本发明提供了一种电晕核微凝胶乳化剂，其特征在于，在特定条件下聚合聚环氧乙烷大分子单体，疏水性单体和交联单体得到的共聚物以及特征性地使用所述乳化剂 乳化。 本发明的目的是提供一种新的电晕核微凝胶乳化剂，其用于制备水乳化组合物，其表现出优异的乳化稳定性，随时间的稳定性和低皮肤刺激性，并且不含粘性 在使用时，呈现露洁的新鲜感，无粉感和/或吱吱声，并且具有优异的香料耐久性，以及用所述乳化剂乳化的水包油型乳化组合物。

公开(公告)号：US11964043B2

公开(公告)日：2024-04-23

申请号：US17362206

申请日：2021-06-29

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Yuki Sugiyama ,  Ryushi Fukuhara ,  Yang Han

IPC: A61K8/91 ,  A61K8/00 ,  A61K8/06 ,  A61K8/81 ,  A61K8/86 ,  A61Q1/00 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  C08F290/06

CPC classification number: A61K8/91 ,  A61K8/00 ,  A61K8/06 ,  A61K8/068 ,  A61K8/81 ,  A61K8/86 ,  A61Q1/00 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  C08F290/06 ,  C08F290/062

Abstract: A method of emulsification of an oil phase in an aqueous continuous phase, by dispersing core-corona microparticles into the aqueous phase, adding the oil phase, and applying shearing force for a time sufficient to emulsify the resulting mixture. The core-corona microparticles are obtained by radical co-polymerization of a polyethylene oxide macromonomer with at least one hydrophobic acrylate monomer and at least one hydrophobic acrylamide monomer.

公开(公告)号：US11931448B2

公开(公告)日：2024-03-19

申请号：US17283692

申请日：2019-10-07

Applicant: Shiseido Company, Ltd.

Inventor： Ryushi Fukuhara ,  Yuki Sugiyama ,  Takumi Watanabe

IPC: A61K8/81 ,  A61K8/04 ,  A61K8/894 ,  A61Q1/02 ,  A61Q19/00

CPC classification number: A61K8/894 ,  A61K8/8147 ,  A61K8/8164 ,  A61Q19/00

Abstract: A water-in-oil emulsion composition that is significantly excellent in emulsification stability, and also excellent in non-stickiness is provided. The water-in-oil emulsion composition includes (a) a polyoxyalkylene/alkyl co-modified silicone; (b) a core-corona particle; (c) an oil-phase component; and (d) an aqueous-phase component.

公开(公告)号：US11285096B2

公开(公告)日：2022-03-29

申请号：US16982315

申请日：2019-03-22

Applicant: Shiseido Company, Ltd.

Inventor： Yuki Sugiyama ,  Ryushi Fukuhara

IPC: A61K8/91 ,  C08F290/06 ,  A61K8/06 ,  A61K8/02 ,  A61Q19/00

Abstract: Provided are a raw material for a cosmetic and an oil-in-water emulsion cosmetic comprising a core-corona polymer particle excellent in emulsion stability and feeling of use. Certain embodiments of the present invention provides a raw material for a cosmetic, comprising a core-corona polymer particle dispersion obtained by radical-polymerizing a polyethylene oxide macromonomer represented by formula (1) and one or two or more of hydrophobic monomers represented by formulas (2) and (3) under conditions (A) to (D).

公开(公告)号：US10945942B2

公开(公告)日：2021-03-16

申请号：US15501989

申请日：2015-06-30

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Yuki Sugiyama ,  Hirohito Shirakami ,  Kazuyuki Miyazawa

IPC: A61K8/04 ,  A61K8/81 ,  A61K8/86 ,  A61Q19/00 ,  A61K8/34 ,  A61Q5/06 ,  A61K8/06 ,  A61K8/31 ,  A61K8/36 ,  A61K8/58 ,  A61Q1/00 ,  A61Q17/04 ,  A61Q19/02 ,  A61Q19/10

Abstract: A starting (raw) material, for cosmetics, comprising a core corona type microgel dispersion obtained by radical polymerization of a specific polyethylene oxide macromonomer, a specific hydrophobic monomer, and a specific cross-linking monomer under specific conditions. The purpose of the present invention is to provide the raw material for cosmetics, with which the cosmetic having a high stability provides a good feeling in use and does not cause skin irritation, can be easily produced.

公开(公告)号：US09539554B2

公开(公告)日：2017-01-10

申请号：US14851195

申请日：2015-09-11

Applicant: Shiseido Company, Ltd.

Inventor： Yuki Sugiyama ,  Tomoko Sato ,  Ken Shoji

IPC: A61K8/06 ,  A61K8/81 ,  A61Q13/00 ,  B01F17/00 ,  A61Q19/00 ,  C08F290/06 ,  C08F220/18 ,  C11B9/00 ,  A61K8/91 ,  C08F220/14 ,  C08F220/28 ,  C08L33/10 ,  C08L33/12 ,  A61Q17/04

CPC classification number: B01F17/0028 ,  A61K8/062 ,  A61K8/8152 ,  A61K8/91 ,  A61K2800/10 ,  A61K2800/54 ,  A61K2800/95 ,  A61Q13/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/005 ,  B01F17/0021 ,  C08F220/14 ,  C08F220/18 ,  C08F220/28 ,  C08F290/062 ,  C08L33/10 ,  C08L33/12 ,  C11B9/00 ,  C08F2220/1825 ,  C08F2220/286 ,  C08F2222/1013

Abstract: The present invention provides a corona-core microgel emulsifying agent composed of a copolymer obtained by polymerizing polyethylene oxide macromonomers, hydrophobic monomers, and cross-linking monomers under specific conditions as well as an oil-in-water emulsified composition characteristically using said emulsifying agent for emulsification.The object of the present invention is to provide a new corona-core microgel emulsifying agent to be used to prepare an oil-in-water emulsified composition that manifests superior emulsification stability, stability over time, and low skin irritation, and is free of stickiness at the time of application, manifests dewy freshness, is free of powdery sensation and/or squeakiness, and is superior in durability of fragrance, as well as an oil-in-water emulsified composition emulsified with said emulsifying agent.

Abstract translation: 本发明的目的是提供一种新的电晕核微凝胶乳化剂，其用于制备水乳化组合物，其表现出优异的乳化稳定性，随时间的稳定性和低皮肤刺激性，并且不含粘性 在使用时，呈现露洁的新鲜感，无粉感和/或吱吱声，并且具有优异的香料耐久性，以及用所述乳化剂乳化的水包油型乳化组合物。

公开(公告)号：US11596583B2

公开(公告)日：2023-03-07

申请号：US16982348

申请日：2019-03-22

Applicant: Shiseido Company, Ltd.

Inventor： Yuki Sugiyama ,  Ryushi Fukuhara

IPC: A61K8/02 ,  A61K8/06 ,  A61K8/85 ,  A61Q19/00

Abstract: Provided are: a core-corona polymer particle excellent in emulsion stability and feeling of use, and a raw material for a cosmetic and an oil-in-water emulsion cosmetic comprising the particle. Certain embodiments of the present invention provides a core-corona polymer particle obtained by radical-polymerizing a polyethylene oxide macromonomer represented by formula (1) and one or two or more of hydrophobic monomers represented by formulas (2) and (3) under conditions (A) to (D).