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1.发明申请公开(公告)号：US20190060242A1
公开(公告)日：2019-02-28
申请号：US15766729
申请日：2016-10-07
发明人： Babu PADMANABHAN , Himadri SEN , Indu BHUSHAN , Vijay KULKARNI , Rakshith SHETTY , Aravind Kumar GURRAM
IPC分类号： A61K9/20 , A61K31/403 , A61J3/10 , A61K31/4985
摘要： A rapidly disintegrating tablet comprising a therapeutically effective amount of a DPP-IV inhibitor and an acid-base couple having mineral content below the daily intake limits is disclosed. The rapidly disintegrating tablet has a sodium content less than 10 mg and a potassium content less than 15 mg. A process for preparation of the rapidly disintegrating tablet comprising the DPP-IV inhibitor is also disclosed.
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公开(公告)号：US20220298020A1
公开(公告)日：2022-09-22
申请号：US17805836
申请日：2022-06-07
发明人： Indu BHUSHAN , Vinay RAO , Rakshith SHETTY
摘要： The present disclosure relates to a method for chemically modifying particles of a bicarbonate salt in a co-rotating twin-screw extruder and chemically modified bicarbonate particles prepared therefrom. The present disclosure also relates to a method for controlling an amount of carbonate salt formed during chemical modification of bicarbonate salt particles.
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公开(公告)号：US20180360737A1
公开(公告)日：2018-12-20
申请号：US15781090
申请日：2016-12-12
发明人： Indu BHUSHAN , Vijay KULKARNI , Rakshith SHETTY
IPC分类号： A61K9/46 , A61K31/155 , A61P3/10
摘要： The present invention relates to effervescent compositions of Metformin and optionally other anti-diabetic agents and processes for preparation thereof. More particularly provides an effervescent composition comprising Metformin, an acid and a base such that the composition is free of affirmatively added binders and granulating solvents. The effervescent composition of the present invention has retained carbon dioxide content of at least 90% of the input blend.
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