公开(公告)号：US20150072974A1

公开(公告)日：2015-03-12

申请号：US14399334

申请日：2013-05-09

Applicant: SUNOVION PHARMACEUTICALS INC.

Inventor： Phillip G. Jones ,  Robert Lew ,  Kerry L. Spear ,  Linghong Xie

IPC: C07D513/04 ,  A61K31/4985 ,  A61K31/496 ,  A61K31/519 ,  C07D401/14 ,  A61K31/437 ,  C07D471/04 ,  C07D401/12 ,  A61K31/4709 ,  A61K45/06 ,  A61K31/551 ,  A61K31/4375

CPC classification number: C07D513/04 ,  A61K31/437 ,  A61K31/4375 ,  A61K31/444 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/519 ,  A61K31/551 ,  A61K45/06 ,  C07D215/26 ,  C07D231/56 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D471/04 ,  C07D495/04 ,  C07D519/00

Abstract: Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and neurological disorders, including, but not limited to, e.g., psychosis, schizophrenia, depression, movement disorders, and Parkinson's disease.

Abstract translation: 本文提供了杂芳基化合物，其合成方法，包含该化合物的药物组合物及其用途。 在一个实施方案中，本文提供的化合物可用于治疗，预防和/或治疗各种疾病，例如CNS障碍和神经障碍，包括但不限于例如精神病，精神分裂症，抑郁症，运动障碍， 和帕金森病。

公开(公告)号：US20190031685A1

公开(公告)日：2019-01-31

申请号：US15947343

申请日：2018-04-06

Applicant: SUNOVION PHARMACEUTICALS INC.

Inventor： Philip G. Jones ,  Robert Lew ,  Kerry L. Spear ,  Linghong Xie

IPC: C07D513/04 ,  A61K31/4985 ,  C07D401/04 ,  A61K31/437 ,  C07D401/12 ,  A61K31/444 ,  A61K31/4375 ,  C07D495/04 ,  A61K31/519 ,  A61K31/4709 ,  C07D231/56 ,  A61K31/496 ,  C07D215/26 ,  C07D471/04 ,  A61K45/06 ,  A61K31/551 ,  C07D401/14 ,  C07D519/00

Abstract: Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and neurological disorders, including, but not limited to, e.g., psychosis, schizophrenia, depression, movement disorders, and Parkinson's disease.

公开(公告)号：US09951088B2

公开(公告)日：2018-04-24

申请号：US14399334

申请日：2013-05-09

Applicant: SUNOVION PHARMACEUTICALS INC.

Inventor： Philip G. Jones ,  Robert Lew ,  Kerry L. Spear ,  Linghong Xie

IPC: A61K31/506 ,  C07D513/04 ,  C07D471/04 ,  C07D401/14 ,  C07D215/26 ,  C07D231/56 ,  C07D401/04 ,  C07D401/12 ,  C07D495/04 ,  C07D519/00 ,  A61K31/437 ,  A61K31/4375 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/519 ,  A61K31/551 ,  A61K45/06 ,  A61K31/444

CPC classification number: C07D513/04 ,  A61K31/437 ,  A61K31/4375 ,  A61K31/444 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/519 ,  A61K31/551 ,  A61K45/06 ,  C07D215/26 ,  C07D231/56 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D471/04 ,  C07D495/04 ,  C07D519/00

Abstract: Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and neurological disorders, including, but not limited to, e.g., psychosis, schizophrenia, depression, movement disorders, and Parkinson's disease.