公开(公告)号：US20190031685A1

公开(公告)日：2019-01-31

申请号：US15947343

申请日：2018-04-06

Applicant: SUNOVION PHARMACEUTICALS INC.

Inventor： Philip G. Jones ,  Robert Lew ,  Kerry L. Spear ,  Linghong Xie

IPC: C07D513/04 ,  A61K31/4985 ,  C07D401/04 ,  A61K31/437 ,  C07D401/12 ,  A61K31/444 ,  A61K31/4375 ,  C07D495/04 ,  A61K31/519 ,  A61K31/4709 ,  C07D231/56 ,  A61K31/496 ,  C07D215/26 ,  C07D471/04 ,  A61K45/06 ,  A61K31/551 ,  C07D401/14 ,  C07D519/00

Abstract: Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and neurological disorders, including, but not limited to, e.g., psychosis, schizophrenia, depression, movement disorders, and Parkinson's disease.

公开(公告)号：US09951088B2

公开(公告)日：2018-04-24

申请号：US14399334

申请日：2013-05-09

Applicant: SUNOVION PHARMACEUTICALS INC.

Inventor： Philip G. Jones ,  Robert Lew ,  Kerry L. Spear ,  Linghong Xie

IPC: A61K31/506 ,  C07D513/04 ,  C07D471/04 ,  C07D401/14 ,  C07D215/26 ,  C07D231/56 ,  C07D401/04 ,  C07D401/12 ,  C07D495/04 ,  C07D519/00 ,  A61K31/437 ,  A61K31/4375 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/519 ,  A61K31/551 ,  A61K45/06 ,  A61K31/444

CPC classification number: C07D513/04 ,  A61K31/437 ,  A61K31/4375 ,  A61K31/444 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/519 ,  A61K31/551 ,  A61K45/06 ,  C07D215/26 ,  C07D231/56 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D471/04 ,  C07D495/04 ,  C07D519/00

Abstract: Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and neurological disorders, including, but not limited to, e.g., psychosis, schizophrenia, depression, movement disorders, and Parkinson's disease.