公开(公告)号：US10792371B2

公开(公告)日：2020-10-06

申请号：US15884963

申请日：2018-01-31

Applicant: Samsung Electronics Co., Ltd.

Inventor： Su Young Chae ,  Sunghyun Kim ,  Eun Ko ,  Yun Ju Jeong ,  Jae Hyun Choi

IPC: C07K16/00 ,  A61K39/00 ,  A61K47/68

Abstract: Provided is a conjugate including a c-Met targeting compound and a bioactive material and methods of use of the conjugate.

公开(公告)号：US20150335669A1

公开(公告)日：2015-11-26

申请号：US14717753

申请日：2015-05-20

Applicant: Samsung Electronics Co., Ltd.

Inventor： Su Young Chae ,  Sunghyun Kim ,  Sang Ok Song ,  Jae Il Lee

IPC: A61K31/704 ,  C07K16/40 ,  A61K47/48

CPC classification number: A61K31/704 ,  A61K47/60 ,  A61K47/6809 ,  A61K47/6871 ,  C07K16/2863 ,  C07K2317/14 ,  C07K2317/24 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/622 ,  C07K2317/92 ,  C07K2317/94

Abstract: Provided is a chemically modified targeting protein, a pharmaceutical composition including the chemically modified targeting protein, a conjugate including the chemically modified targeting protein and a drug, and methods for preparing the same.

Abstract translation: 提供了化学修饰的靶向蛋白质，包含化学修饰的靶向蛋白质的药物组合物，包含化学修饰的靶向蛋白质和药物的缀合物及其制备方法。

公开(公告)号：US20150071950A1

公开(公告)日：2015-03-12

申请号：US14485062

申请日：2014-09-12

Applicant: Samsung Electronics Co., Ltd.

Inventor： Su Young Chae ,  Sunghyun Kim ,  Eun Ko ,  Yun Ju Jeong ,  Jae Hyun Choi

IPC: A61K47/48 ,  A61K31/337

CPC classification number: A61K47/6859 ,  A61K47/6803 ,  A61K47/6851

Abstract: Disclosed is a conjugate in which a c-Met targeting compound and a bioactive material are chemically conjugated with each other, and methods of use thereof.

Abstract translation: 公开了一种其中c-Met靶向化合物和生物活性物质彼此化学共轭的缀合物及其使用方法。

公开(公告)号：US20180236097A1

公开(公告)日：2018-08-23

申请号：US15884963

申请日：2018-01-31

Applicant: Samsung Electronics Co., Ltd.

Inventor： Su Young Chae ,  Sunghyun Kim ,  Eun Ko ,  Yun Ju Jeong ,  Jae Hyun Choi

IPC: A61K47/68

Abstract: Provided is a conjugate including a c-Met targeting compound and a bioactive material and methods of use of the conjugate.

公开(公告)号：US10159690B2

公开(公告)日：2018-12-25

申请号：US14717753

申请日：2015-05-20

Applicant: Samsung Electronics Co., Ltd.

Inventor： Su Young Chae ,  Sunghyun Kim ,  Sang Ok Song ,  Jae Il Lee

IPC: A61K47/60 ,  A61K47/68 ,  C07K16/28 ,  A61K31/704

Abstract: Provided is a chemically modified targeting protein, a pharmaceutical composition including the chemically modified targeting protein, a conjugate including the chemically modified targeting protein and a drug, and methods for preparing the same.

公开(公告)号：US09889206B2

公开(公告)日：2018-02-13

申请号：US14485062

申请日：2014-09-12

Applicant: Samsung Electronics Co., Ltd.

Inventor： Su Young Chae ,  Sunghyun Kim ,  Eun Ko ,  Yun Ju Jeong ,  Jae Hyun Choi

IPC: A61K39/395 ,  A61K47/48

CPC classification number: A61K47/6859 ,  A61K47/6803 ,  A61K47/6851

Abstract: Disclosed is a conjugate in which a c-Met targeting compound and a bioactive material are chemically conjugated with each other, and methods of use thereof.