Simple Tests for Rapid Detection of Canine Parvovirus Antigen and Antibodies
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    发明申请
    Simple Tests for Rapid Detection of Canine Parvovirus Antigen and Antibodies 审中-公开
    用于快速检测犬细小病毒抗原和抗体的简单测试

    公开(公告)号:US20100137159A1

    公开(公告)日:2010-06-03

    申请号:US12606451

    申请日:2009-10-27

    IPC分类号: C12Q1/70 C40B30/04

    摘要: Slide agglutination tests (SATs) and slide inhibition tests (SITs) provide rapid detection, quantitation and strain identification of red blood cell (RBC) agglutinating viruses such as canine parvovirus (CPV) in biological samples. The tests are rapid, low-cost, and easy to use. These tests do not require any expensive equipment and can thus be used to monitor infections and antibody titers under field conditions. The tests can be modified to detect results using fluorescence (FSAT). FSAT is useful for rapid high-throughput screening (HTS) of libraries of small molecules and/or chemical compounds to identify antiviral compounds useful for the treatment of diseases caused by emerging hemaglutinating viruses that infect animals and humans.

    摘要翻译: 幻灯片凝集试验(SAT)和幻灯片抑制试验(SITs)可提供生物样品中红细胞(RBC)凝集病毒如犬细小病毒(CPV)的快速检测,定量和毒株鉴定。 测试速度快,成本低,易于使用。 这些测试不需要任何昂贵的设备,因此可用于监测现场条件下的感染和抗体滴度。 可以修改测试以使用荧光(FSAT)检测结果。 FSAT可用于小分子和/或化学化合物文库的快速高通量筛选(HTS),以鉴定可用于治疗由感染动物和人类的新出现的血液流感病毒引起的疾病的抗病毒化合物。