公开(公告)号：US11774366B2

公开(公告)日：2023-10-03

申请号：US16986108

申请日：2020-08-05

Applicant: Seagate Technology LLC

Inventor： Gemma Mendonsa ,  Eric K. Wadleigh ,  Vivek Krishnamurthy ,  Riyan A. Mendonsa ,  Martin G. Blaber ,  Krishnan Subramanian

IPC: C12Q1/6869 ,  G01N21/65 ,  C12N9/12 ,  G01N27/447 ,  B82Y30/00

CPC classification number: G01N21/658 ,  C12N9/1252 ,  C12Q1/6869 ,  G01N27/44786 ,  B82Y30/00

Abstract: A Surface-Enhanced Raman Spectroscopy (SERS) device to perform accurate label-free long-read DNA sequencing. A Raman sensor has a hot spot defined by plasmonic nanostructures and excited by at least one laser. An immobilized DNA polymerase can be used to pull a DNA template strand to be sequenced through the hot spot.

公开(公告)号：US20210148828A1

公开(公告)日：2021-05-20

申请号：US16986108

申请日：2020-08-05

Applicant: Seagate Technology LLC

Inventor： Gemma Mendonsa ,  Eric K. Wadleigh ,  Vivek Krishnamurthy ,  Riyan A. Mendonsa ,  Martin G. Blaber ,  Krishnan Subramanian

IPC: G01N21/65 ,  C12N9/12 ,  C12Q1/6869 ,  G01N27/447

Abstract: A Surface-Enhanced Raman Spectroscopy (SERS) device to perform accurate label-free long-read DNA sequencing. A Raman sensor has a hot spot defined by plasmonic nanostructures and excited by at least one laser. An immobilized DNA polymerase can be used to pull a DNA template strand to be sequenced through the hot spot.