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公开(公告)号：US20130156694A1
公开(公告)日：2013-06-20
申请号：US13716087
申请日：2012-12-15
申请人： Sergei B. Onikienko , Alex Nivorozhkin , Alexander V. Zemlyanoi , Mikhail Viktorovich Shorokhov , Vladimir Ivanovich Pereguda , Valery Aleksandrovich Chereshnev
发明人： Sergei B. Onikienko , Alex Nivorozhkin , Alexander V. Zemlyanoi , Mikhail Viktorovich Shorokhov , Vladimir Ivanovich Pereguda , Valery Aleksandrovich Chereshnev
IPC分类号： C07K14/435 , C07K16/46
CPC分类号： C07K14/47 , A61K38/1709 , C07K14/435 , C07K16/46 , C07K2319/00 , C07K2319/30 , C07K2319/50
摘要： The present invention relates to novel therapies that utilize HSP70 fusion proteins for the treatment of disorders or conditions regulated by HSP70.
摘要翻译： 本发明涉及利用HSP70融合蛋白治疗由HSP70调节的病症或病症的新疗法。
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公开(公告)号：US09217018B2
公开(公告)日：2015-12-22
申请号：US13716087
申请日：2012-12-15
申请人： Sergei B Onikienko , Alex Nivorozhkin , Alexander V Zemlyanoi , Mikhail Viktorovich Shorokhov , Vladimir Ivanovich Pereguda , Valery Aleksandrovich Chereshnev
发明人： Sergei B Onikienko , Alex Nivorozhkin , Alexander V Zemlyanoi , Mikhail Viktorovich Shorokhov , Vladimir Ivanovich Pereguda , Valery Aleksandrovich Chereshnev
CPC分类号： C07K14/47 , A61K38/1709 , C07K14/435 , C07K16/46 , C07K2319/00 , C07K2319/30 , C07K2319/50
摘要： The present invention relates to novel therapies that utilize HSP70 fusion proteins for the treatment of disorders or conditions regulated by HSP70.
摘要翻译： 本发明涉及利用HSP70融合蛋白治疗由HSP70调节的病症或病症的新疗法。
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3.发明授权公开(公告)号：US09616100B2
公开(公告)日：2017-04-11
申请号：US14333483
申请日：2014-07-16
CPC分类号： A61K38/17 , A61K38/1703 , A61K47/60
摘要： The present invention relates to novel therapies that utilize exogenous HSP70 for the treatment of disorders or conditions regulated by HSP70 through administration of exogenous HSP70.
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4.发明申请NOVEL METHODS OF USE OF HSP70 FOR INCREASED PERFORMANCE OR TREATMENT OF HSP70 RELATED DISORDERS 审中-公开HSP70用于增加HSP70相关疾病的性能或治疗的新方法公开(公告)号：US20130090294A1
公开(公告)日：2013-04-11
申请号：US13536542
申请日：2012-06-28
IPC分类号： A61K38/17
CPC分类号： A61K38/17 , A61K38/1703 , A61K47/60
摘要： The present invention relates to novel therapies that utilize exogenous HSP70 for the treatment of disorders or conditions regulated by HSP70 through administration of exogenous HSP70.
摘要翻译： 本发明涉及利用外源性HSP70治疗通过施用外源HSP70而由HSP70调节的病症或病症的新疗法。
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5.发明申请NOVEL METHODS OF USE OF HSP70 FOR INCREASED PERFORMANCE OR TREATMENT OF HSP70 RELATED DISORDERS 审中-公开HSP70用于增加HSP70相关疾病的性能或治疗的新方法公开(公告)号：US20140329764A1
公开(公告)日：2014-11-06
申请号：US14333483
申请日：2014-07-16
CPC分类号： A61K38/17 , A61K38/1703 , A61K47/60
摘要： The present invention relates to novel therapies that utilize exogenous HSP70 for the treatment of disorders or conditions regulated by HSP70 through administration of exogenous HSP70.
摘要翻译： 本发明涉及利用外源性HSP70治疗通过施用外源HSP70而由HSP70调节的病症或病症的新疗法。
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公开(公告)号：US09937241B2
公开(公告)日：2018-04-10
申请号：US13651416
申请日：2012-10-13
CPC分类号： A61K38/46 , A61K9/0075 , A61K9/1617 , A61K9/1647 , A61K38/1709 , A61K47/60
摘要： The present invention relates to novel therapies that utilize stabilized exogenous HSP70 for the treatment of disorders or conditions regulated by HSP70 through administration of degradation resistant formulations of HSP70. Furthermore, the present invention is directed to methods comprising the administration of stabilized exogenous HSP70 for use in the treatment of HSP70 related disorders or conditions, for example, for increased endurance or alleviating fatigue syndrome.
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公开(公告)号：US20130101573A1
公开(公告)日：2013-04-25
申请号：US13651416
申请日：2012-10-13
IPC分类号： A61K38/46
CPC分类号： A61K38/46 , A61K9/0075 , A61K9/1617 , A61K9/1647 , A61K38/1709 , A61K47/60
摘要： The present invention relates to novel therapies that utilize stabilized exogenous HSP70 for the treatment of disorders or conditions regulated by HSP70 through administration of degradation resistant formulations of HSP70. Furthermore, the present invention is directed to methods comprising the administration of stabilized exogenous HSP70 for use in the treatment of HSP70 related disorders or conditions, for example, for increased endurance or alleviating fatigue syndrome
摘要翻译： 本发明涉及利用稳定的外源性HSP70治疗由HSP70调节的病症或病症通过施用耐HSP70降解抗性制剂的新疗法。 此外，本发明涉及包含施用稳定的外源HSP70以用于治疗HSP70相关疾病或病症的方法，例如用于增加耐力或减轻疲劳综合征
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公开(公告)号：US20100035886A1
公开(公告)日：2010-02-11
申请号：US12402694
申请日：2009-03-12
IPC分类号： A61K31/4985 , A61P3/10 , A61P3/04
CPC分类号： A61K31/48 , A61K9/0012 , A61K9/0014 , A61K9/0019 , A61K9/0043 , A61K9/0056 , A61K9/006 , A61K9/06 , A61K9/12 , A61K9/1617 , A61K9/1635 , A61K9/1652 , A61K9/2018 , A61K9/2027 , A61K9/205 , A61K9/2054 , A61K9/2077 , A61K9/209 , A61K9/7007 , A61K31/00 , A61K31/135 , A61K31/366 , A61K31/403 , A61K31/485 , A61K31/4985 , A61K31/55 , A61K45/06 , A61K47/10 , A61K47/26 , A61K47/36 , A61K47/44 , A61K2300/00
摘要： This invention relates to stable pharmaceutical compositions for parenteral administration comprising dopamine agonists and peripheral acting agents useful for treatment of metabolic disorders or key elements thereof. The parenteral dosage forms exhibit long stable shelf life and distinct pharmacokinetics.
摘要翻译： 本发明涉及用于肠胃外给药的稳定的药物组合物，其包含可用于治疗代谢紊乱或其关键要素的多巴胺激动剂和外周作用剂。 肠胃外剂型显示长期稳定的保质期和明显的药代动力学。
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公开(公告)号：US20050159467A1
公开(公告)日：2005-07-21
申请号：US11030536
申请日：2005-01-06
申请人： Alex Nivorozhkin , John Van Duzer , Andrew Salzman , Garry Southan , Siya Ram , Qi Zeng , Csaba Szabo
发明人： Alex Nivorozhkin , John Van Duzer , Andrew Salzman , Garry Southan , Siya Ram , Qi Zeng , Csaba Szabo
IPC分类号： A61K31/41 , A61K31/427 , A61K31/4439 , A61K31/496 , A61K31/5377 , A61P1/00 , A61P1/02 , A61P1/04 , A61P3/10 , A61P9/00 , A61P11/06 , A61P13/12 , A61P17/06 , A61P19/02 , A61P19/06 , A61P25/28 , A61P27/00 , A61P29/00 , A61P37/06 , A61P43/00 , C07D257/04 , C07D401/10 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D417/12 , A61K31/454 , C07D413/02 , C07D43/02
CPC分类号： C07D257/04 , C07D401/10 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D417/12
摘要： The present invention relates to 5-Aryltetrazole Compounds, compositions comprising an effective amount of a a 5-Aryltetrazole Compound, and methods for treating an inflammation disease, a reperfusion disease, or hyperuricemia in an animal in need thereof comprising administering to the animal an effective amount of a 5-Aryltetrazole compound.
摘要翻译： 本发明涉及5-芳基四唑化合物，包含有效量的5-芳基四唑化合物的组合物，以及用于治疗有需要的动物的炎症疾病，再灌注疾病或高尿酸血症的方法，其包括向所述动物施用有效量 的5-芳基四唑化合物。
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公开(公告)号：US07135491B2
公开(公告)日：2006-11-14
申请号：US11030536
申请日：2005-01-06
申请人： Alex Nivorozhkin , John Van Duzer , Andrew Salzman , Garry Southan , Siya Ram , Qi Zeng , Csaba Szabo
发明人： Alex Nivorozhkin , John Van Duzer , Andrew Salzman , Garry Southan , Siya Ram , Qi Zeng , Csaba Szabo
IPC分类号： A61K31/41
CPC分类号： C07D257/04 , C07D401/10 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/12 , C07D417/12
摘要： The present invention relates to 5-Aryltetrazole Compounds, compositions comprising an effective amount of a a 5-Aryltetrazole Compound, and methods for treating an inflammation disease, a reperfusion disease, or hyperuricemia in an animal in need thereof comprising administering to the animal an effective amount of a 5-Aryltetrazole compound.
摘要翻译： 本发明涉及5-芳基四唑化合物，包含有效量的5-芳基四唑化合物的组合物，以及用于治疗有需要的动物的炎症疾病，再灌注疾病或高尿酸血症的方法，其包括向所述动物施用有效量 的5-芳基四唑化合物。
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