公开(公告)号：US20190194163A1

公开(公告)日：2019-06-27

申请号：US16322278

申请日：2016-08-04

Applicant: Sunovion Pharmaceuticals Inc.

Inventor： Michele L.R. HEFFERNAN ,  Larry Wendell HARDY ,  Scott P. BROWN ,  Lee W. HERMAN

IPC: C07D401/08 ,  C07D405/06 ,  C07D401/06 ,  C07D401/14 ,  C07D207/12 ,  C07D295/096 ,  C07D295/027 ,  C07D311/22 ,  C07D471/04 ,  C07D235/12 ,  C07D237/14 ,  C07D217/24 ,  C07D295/073 ,  C07D295/108 ,  C07D275/04 ,  C07D311/08 ,  C07D307/83 ,  C07D491/048 ,  C07D277/66 ,  C07D401/12 ,  C07D211/44 ,  C07D211/58 ,  C07D265/30 ,  C07D413/06 ,  C07D241/04 ,  C07D223/08 ,  C07D267/10 ,  C07D243/08 ,  C07D413/08 ,  C07D471/08 ,  C07D487/10 ,  C07D471/10 ,  C07D491/107

CPC classification number: C07D401/08 ,  A61P25/18 ,  A61P25/28 ,  C07D207/12 ,  C07D207/36 ,  C07D211/42 ,  C07D211/44 ,  C07D211/58 ,  C07D213/81 ,  C07D217/24 ,  C07D221/20 ,  C07D223/08 ,  C07D235/12 ,  C07D237/14 ,  C07D241/04 ,  C07D243/08 ,  C07D249/12 ,  C07D265/30 ,  C07D267/10 ,  C07D275/04 ,  C07D277/66 ,  C07D295/027 ,  C07D295/073 ,  C07D295/088 ,  C07D295/096 ,  C07D295/104 ,  C07D295/108 ,  C07D307/83 ,  C07D311/08 ,  C07D311/22 ,  C07D311/58 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/06 ,  C07D405/06 ,  C07D405/12 ,  C07D413/06 ,  C07D413/08 ,  C07D417/04 ,  C07D471/04 ,  C07D471/08 ,  C07D471/10 ,  C07D487/10 ,  C07D491/048 ,  C07D491/107 ,  C07D491/20 ,  C07D513/04

Abstract: Compounds of formula I: are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disorders in a patient in need are also disclosed. Such disorders include depression, bipolar disorder, pain, schizophrenia, obsessive compulsive disorder, addiction, social disorder, attention deficit hyperactivity disorder, an anxiety disorder, autism, a cognitive impairment, or a neuropsychiatric symptom such as apathy, depression, anxiety, psychosis, aggression, agitation, impulse control disorders, and sleep disorders in neurological disorders such as Alzheimer's and Parkinson's diseases.

公开(公告)号：US20180030064A1

公开(公告)日：2018-02-01

申请号：US15663688

申请日：2017-07-28

Applicant: Sunovion Pharmaceuticals Inc.

Inventor： Linghong XIE ,  Michele L.R. HEFFERNAN ,  Philip Glyn JONES ,  Taleen G. HANANIA

IPC: C07D493/04 ,  C07D313/08 ,  C07D307/87 ,  C07D311/76

CPC classification number: C07D493/04 ,  C07D307/87 ,  C07D311/76 ,  C07D313/08

Abstract: Disclosed are compounds of formula (I): and pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disease and disorders in a subject in need are also disclosed.

公开(公告)号：US20220340588A1

公开(公告)日：2022-10-27

申请号：US17145548

申请日：2021-01-11

Applicant: Sunovion Pharmaceuticals Inc. ,  PGI Drug Discovery LLC

Inventor： Linghong XIE ,  Michele L.R. HEFFERNAN ,  Philip Glyn JONES ,  Taleen G. HANANIA

IPC: C07D493/04 ,  C07D311/76 ,  C07D313/08 ,  C07D307/87

Abstract: Disclosed are compounds of formula (I): and pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disease and disorders in a subject in need are also disclosed.