公开(公告)号：US20220348986A1

公开(公告)日：2022-11-03

申请号：US17620230

申请日：2020-06-19

Applicant: T2 Biosystems, Inc.

Inventor： Jessica Lee SNYDER ,  Joseph MARTURANO ,  Sandy ESTRADA ,  Robert Patrick SHIVERS ,  Roger SMITH ,  Brendan John MANNING ,  Thomas J. LOWERY, Jr. ,  Daniel GAMERO ,  Mohamed Nabuan NAUFER ,  Kelly N. BURGESS

IPC: C12Q1/689 ,  C12Q1/6895

Abstract: Provided herein are methods of amplifying and detecting pathogens and drug resistance markers (e.g., antibiotic resistance genes) in complex samples (e.g., blood), as well as related panels and compositions (e.g., primers, probes, magnetic particles, systems, cartridges, and kits). The methods, panels, and compositions can be used for comprehensive detection of pathogens and drug resistance markers for patient identification, patient selection, optimization of therapies, and antimicrobial stewardship.