公开(公告)号：US20150191486A1

公开(公告)日：2015-07-09

申请号：US14665237

申请日：2015-03-23

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Takanobu KUROITA ,  Yasuhiro IMAEDA ,  Kouichi IWANAGA ,  Naohiro TAYA ,  Hidekazu TOKUHARA ,  YOSHIYUKI FUKASE

IPC: C07D495/04 ,  C07D487/08 ,  C07D405/14 ,  C07D401/12 ,  C07D471/04

CPC classification number: C07D401/12 ,  C07D233/90 ,  C07D401/14 ,  C07D405/14 ,  C07D407/12 ,  C07D409/06 ,  C07D409/14 ,  C07D413/06 ,  C07D413/14 ,  C07D417/06 ,  C07D417/12 ,  C07D453/02 ,  C07D471/04 ,  C07D487/04 ,  C07D487/08 ,  C07D495/04

Abstract: Compounds represented by the formulas wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.

Abstract translation: 由式表示的化合物，其中各符号如说明书中所定义，其前药具有优异的肾素抑制活性，可用作预防或治疗高血压，高血压等各种器官损害的药剂。