公开(公告)号：US20240132467A1

公开(公告)日：2024-04-25

申请号：US18332551

申请日：2023-06-09

Applicant: TMEM16A Limited

Inventor： Stephen COLLINGWOOD ,  Jonathan David Hargrave ,  Duncan Alexander Hay ,  Clive McCarthy ,  Thomas Beauregard Schofield ,  Edward Walker ,  Naomi Went

IPC: C07D401/06 ,  A61P11/12 ,  C07D235/08 ,  C07D235/12 ,  C07D235/16 ,  C07D405/04 ,  C07D413/06

CPC classification number: C07D401/06 ,  A61P11/12 ,  C07D235/08 ,  C07D235/12 ,  C07D235/16 ,  C07D405/04 ,  C07D413/06

Abstract: Compounds of general formula (I): (I) wherein R1, R2, R3, R4, R5, Y and Z are as defined herein are useful for treating respiratory disease and other diseases and conditions modulated by TMEM16A.