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公开(公告)号：US20220395175A1
公开(公告)日：2022-12-15
申请号：US17594912
申请日：2020-04-24
Applicant: Topcon Corporation
Inventor： Yasufumi FUKUMA , Zhenguo WANG , Zaixing MAO , Kazuhiro OOMORI , Makoto FUJINO
Abstract: In an ophthalmologic apparatus, including: an objective lens that faces a subject's eye; an illumination optical system that irradiates a cornea of the subject's eye with illumination light through the objective lens; and a corneal measurement optical system including an interference image capturing camera that takes an image of a corneal reflection light, which is a reflection of the illumination light reflected from the cornea, through the objective lens, a numerical aperture G of the illumination optical system is larger than a numerical aperture g of the corneal measurement optical system.
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公开(公告)号：US20220175247A1
公开(公告)日：2022-06-09
申请号：US17594552
申请日：2020-04-24
Applicant: Topcon Corporation
Inventor： Zhenguo WANG , Zaixing MAO , Kazuhiro OOMORI , Makoto FUJINO
Abstract: An ophthalmologic apparatus includes: an objective lens that faces a subject's eye; an alignment light emitting unit that irradiates the subject's eye with alignment light to perform measurement of alignment between the objective lens and the subject's eye; an alignment reflection light receiving unit that receives alignment reflection light, which is a reflection of the alignment light from the subject's eye; an anterior segment camera that receives corneal reflection light; and a holder positioned between the anterior segment camera and the objective lens to hold the anterior segment camera, wherein the holder includes an imaging transmissive portion that transmits the corneal reflection light to the anterior segment camera, a first light-transmissive portion that transmits the alignment light from the alignment light emitting unit, and a second light-transmissive portion that transmits the alignment reflection light from the subject's eye.
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公开(公告)号：US20250111518A1
公开(公告)日：2025-04-03
申请号：US18726358
申请日：2022-12-23
Applicant: TOPCON CORPORATION
Inventor： Toru ITO , Yasufumi FUKUMA , Zaixing MAO , Hisashi TSUKADA
Abstract: Provided is an object measurement device for measuring the shape of an object by recognizing the object using a machine learning model, automating determination of an edge detection direction and determination of a region for performing edge processing, and performing highly accurate edge extraction in units of sub-pixels, for example. An object measurement device according to the present invention comprises: an object recognition unit that recognizes an object in an image by inputting an acquired image as input data into a trained model, and outputs a region of the object as a recognition result; an edge detection direction determination unit that determines an edge detection direction for the region of the object recognized by the object recognition unit; an edge processing region determination unit that determines an edge processing region for the region of the object recognized by the object recognition unit; and an edge detection unit that performs edge detection in the edge detection direction determined by the edge detection direction determination unit, for the edge processing region determined by the edge processing region determination unit.
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4.发明公开公开(公告)号：US20240266062A1
公开(公告)日：2024-08-08
申请号：US18562777
申请日：2022-05-27
Applicant: RIKEN , SAI Corporation , Topcon Corporation
Inventor： Satoshi WADA , Kei TANEISHI , Yasufumi FUKUMA , Zaixing MAO , Hisashi TSUKADA
IPC: G16H50/30
CPC classification number: G16H50/30
Abstract: Provided are a disease risk evaluation method, a disease risk evaluation system and a health information processing device, whereby it becomes possible to detect the latent onset tendency in a healthy stage in advance and to quantify the prospective disease risk of a disease of interest. Each of the disease risk evaluation method, the disease risk evaluation system and the health information processing device according to the present invention includes a plurality of steps, i.e., a step for classifying into a group in which the susceptibility to developing a specific disease is high and a group in which the susceptibility to developing the specific disease is low regardless of the degree of progression of the disease from a healthy stage until the onset of the disease, and a step for further classifying the degrees of the development of the disease in a group in which the incidence risk is determined as high. Each of the disease risk evaluation method, the disease risk evaluation system and the health information processing device is characterized by being achieved by changing the type of data to be used in a data-driven analysis in each of the steps.
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Patent Agency Ranking
公开(公告)号：US20220248950A1
公开(公告)日：2022-08-11
申请号：US17596330
申请日：2020-06-10
Applicant: Topcon Corporation
Inventor： Zhenguo WANG , Zaixing MAO , Jongsik KIM , Bin CAO , Makoto FUJINO , Kazuhiro OOMORI , Eiichi YANAGI , Ying DONG , Song MEI , Kinpui CHAN
Abstract: An ophthalmologic apparatus includes: an objective lens 18 configured to face a subject's eye E; an illumination optical system 1c configured to irradiate the subject's eye E with illumination light L1; a measurement optical system 1 b configured to take an interference image of corneal reflection light R1, which is a reflection of the illumination light L1, through the objective lens 18; an observation optical system 1a configured to image an anterior segment of the subject's eye E through the objective lens 18; a control unit 2 configured to process information on imaging by the measurement optical system 1b and the observation optical system 1 a; and the control unit 2 configured to simultaneously output, to a single output unit 3, tear film information calculated from the interference image by the measurement optical system 1 b, and information on the anterior segment E imaged by the observation optical system 1a.
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公开(公告)号：US20230306568A1
公开(公告)日：2023-09-28
申请号：US18012667
申请日：2021-06-22
Applicant: Osaka University , Topcon Corporation
Inventor： Kohji NISHIDA , Kazuichi MARUYAMA , Atsuya MIKI , Ryo KAWASAKI , Hirokazu SAKAGUCHI , Chikako HARA , Song MEI , Yasufumi FUKUMA , Zaixing MAO , Zhenguo WANG , Kinpui CHAN
CPC classification number: G06T5/50 , A61B3/102 , A61B3/1225 , G06T7/0014 , G06T7/11 , G06T7/30 , G06T7/60 , G06T2200/04 , G06T2207/10101 , G06T2207/20036 , G06T2207/20212 , G06T2207/30041 , G06T2207/30096 , G06T2207/30101 , G06T2207/30242
Abstract: A medical diagnostic apparatus includes a receiver circuit that receives three-dimensional volumetric data of a subject’s eye, and a processor configured to separate portions of the three-dimensional volumetric data into separate segments, perform processing differently on each of the separate segments, and combine the separately processed segments to produce an enhanced three-dimensional volumetric data set. The processor is further configured to generate at least one diagnostic metric from the enhanced three-dimensional volumetric data set, and the processor is further configured to evaluate a pathological condition based on the at least one diagnostic metric. Related methods and computer readable media are also disclosed.
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公开(公告)号：US20220313075A1
公开(公告)日：2022-10-06
申请号：US17669388
申请日：2022-02-11
Inventor： Zaixing MAO , Kyoko OHNO-MATSUI , Hiroyuki TAKAHASHI , Noriko NAKAO
Abstract: A medical diagnostic apparatus includes a receiver circuit that receives three-dimensional data of an eye, and processing circuitry configured to segment the three-dimensional data into regions that include a target structural element and regions that do not include the target structural element to produce a segmented three-dimensional data set. The segmenting is performed using a plurality of segmentation algorithms. Each of the plurality of segmentation algorithms is trained separately on different two-dimensional data extracted from the three-dimensional data. The processing circuitry is further configured to generate at least one metric from the segmented three-dimensional data set, and evaluate a medical condition based on the at least one metric.
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公开(公告)号：US20200337552A1
公开(公告)日：2020-10-29
申请号：US16845928
申请日：2020-04-10
Applicant: Topcon Corporation
Inventor： Zhenguo WANG , Zaixing MAO , Hideharu SUZUKI , Kazuhiro OOMORI , Makoto FUJINO
Abstract: An ophthalmologic apparatus includes: an ophthalmologic apparatus body having: an objective lens that faces a subject's eye; a first illumination optical system that irradiates a cornea of the subject's eye with illumination light emitted from a first illumination light source along an optical axis overlapping an optical axis center of the objective lens; an interference image capturing camera that takes an image of a corneal reflection light through the objective lens and outputs an imaging signal; and a calculation unit that calculates, based on a corneal reflection image, of a corneal reflection light, input from the interference image capturing camera, a thickness of a tear fluid film at each position on the corneal surface; and a guide rail that supports the ophthalmologic apparatus body. The guide rail supports the ophthalmologic apparatus body in a rotatable manner such that an optical axis center of the objective lens is positioned obliquely with respect to a horizontal direction orthogonal to a gravity direction.
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公开(公告)号：US20200337551A1
公开(公告)日：2020-10-29
申请号：US16845747
申请日：2020-04-10
Applicant: Topcon Corporation
Inventor： Zhenguo WANG , Zaixing MAO , Kazuhiro OOMORI , Makoto FUJINO
Abstract: An ophthalmologic apparatus includes: an objective lens that faces a subject's eye; a first illumination optical system that irradiates a cornea of the subject's eye with illumination light; and a corneal measurement optical system having an imaging element that takes an image of a corneal reflection light, which is a reflection of the illumination light, through the objective lens, and outputs an imaging signal. The corneal measurement optical system includes a first mirror arranged near the objective lens and a second mirror arranged near the imaging element. The first and second mirrors and are configured such that the corneal reflection light that enters and is reflected from the first mirror, and then enters and is reflected from the second mirror exits toward an incident side from which the corneal reflection light enters a reflection surface of the first mirror.
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